Chemokines, cytokines, and complements are all expressed in amyloid plaques. In vitro, Aβ induces innate immune expression. Aβ clearance is aided by microglia
As a therapeutic approach, activation of the adaptive immune system against Aβ peptide will aid clearance
Declarations
Acknowledgments
Thanks are due to CEHTI and the bioinformatics lab of the Department of Biotechnology and Bioinformatics, Jaypee University of Information technology, Solan, Himachal Pradesh, India for the technical help.
Author contributions
TRS: Conceptualization, Writing—review & editing. AS: Writing—original draft, Writing—review & editing. All authors read and approved the submitted version.
Conflicts of interest
The authors declare that they have no conflicts of interest.
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