Table Info

Table 4.

Possible associations between antidepressants and infection risk

Mechanism or outcome	Evidence
Immunosuppression	Reduced leukocyte count [131] Reduced CD4+ count [119, 121] Reduced immune response in burns patients [132] Impaired tumor surveillance [140]
Increased colonization	Increased nasal bacterial colonization [138]
Increased infection risk	Infections in general [133] Post-operative infections [134] Respiratory infections [136] Clostridium difficile infection [135]
Worse outcomes after infection	Increased mortality in hospitalized patients [137]
Antimicrobial resistance	Selection pressure towards antibiotic resistance in Escherichia coli [139]

Declarations

Author contributions

RPR: Conceptualization, Methodology, Writing—original draft, Writing—review & editing. The author has read and approved the submitted version.

Conflicts of interest

The author declares that he has no conflicts of interest.

Ethical approval

Not applicable.

Consent to participate

Not applicable.

Consent to publication

Not applicable.

Availability of data and materials

Not applicable.

Funding

Not applicable.

Copyright

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