Recent miRNA-related studies in AIS
| Types | Year | Abstract | Reference |
|---|---|---|---|
| miR-20a-3p | 2022 | Identify the neuroprotective effect of miR-20a-3p based on the astrocytes | [82] |
| miR-126a-5p | 2021 | miR-126a-5p is a novel potential target for ischemic stroke therapy due to its protection against cerebral I/R injury via directly targeting nicotinamide adenine dinucleotide phosphate oxidase 2 (NOX2) | [83] |
| miR-190 | 2021 | miR-190 confers protection against brain I/R injury by modulating Rho/Rho-kinase signaling | [84] |
| miR-30c | 2020 | miR-30c can improve the pathological damage of rats with I/R injury and plays a neuroprotective role both in vivo and in vitro by targeting SRY-box transcription factor 9 (SOX9) | [85] |
| miR-22 | 2020 | miR-22 exerts its neuroprotective and angiogenic functions via the PI3K/Akt signaling pathway, at least partly, in rats under cerebral ischemia-reperfusion | [86] |
| miR-1202 | 2020 | miR-1202 exerts a neuroprotective effect by negatively regulating its target protein Rab1a, which can inactivate TLR4/NF-κB-involved inflammatory signaling pathway in OGD/reoxygenation (R) induced human microglia (HM) cells | [87] |
| miR-532-5p | 2020 | These findings reveal that miR-532-5p protects against ischemic stroke by inhibiting phosphatase and tensin homolog (PTEN) and activating the PI3K/Akt signaling pathway stroke | [88] |
| miR-18b | 2020 | These data indicate that miR-18b protects against cerebral I/R injury by inhibiting annexin A3 (ANXA3) and activating PI3K/Akt pathway | [89] |
| miR-219a-5p | 2020 | Upregulation of miR-219a-5p decreases cerebral I/R injury by targeting phosphodiesterase 4D (Pde4d) in vitro | [90] |
| miR-193b-3p | 2020 | miR-193b-3p has a potentially neuroprotective effect on focal cerebral I/R injury by inhibiting 5-lipoxygenase (5-LOX) expression | [91] |
