Genetic variants associated with ASM safety
| Gene variant | Associated drug | Severe adverse reactions | Ethnic group | Reference |
|---|---|---|---|---|
| HLA-B*1502 | Carbamazepine (CBZ) | Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) | Han-Chinese, Thai, and Malaysian | [34] |
| HLA-A*3101 | Carbamazepine (CBZ) | Hypersensitivity reactions | European populations | [35] |
AS: Conceptualization, Writing—original draft. KH: Writing—original draft, Writing—review & editing. A Zafar: Validation, Writing—review & editing. A Zainab: Conceptualization, Writing—original draft, Writing—review & editing. SA: Conceptualization, Supervision. All authors read and approved the submitted version.
The authors declare that they have no conflicts of interest.
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© The Author(s) 2024.