Results of motor and cognitive performance (median, min–max) in the dual-task experiment in group comparison: Cognitive performance was measured by the number of arithmetic steps completed with and without a motor challenge (with eyes open and closed, respectively), as well as the total number of arithmetic steps. Motor performance was measured by the mean speed of body sway in °/s (MSV3D) under the single-task, motor challenge, cognitive challenge, and combined task conditions

FeatureHCpwMSTest value* (P)
Motor feature
MSV3D single task in °/s0.21 (0.11–0.35)0.26 (0.08–1.01)1,264 (< 0.0001)
MSV3D motor challenge in °/s0.30 (0.11–0.51)0.44 (0.16–1.89)1,045 (< 0.0001)
MSV3D cognitive challenge in °/s0.25 (0.07–1.13)0.41 (0.12–3.98)1,576 (0.001)
MSV3D combined task in °/s0.29 (0.11–1.25)0.45 (0.10–2.31)1,315 (< 0.0001)
Cognitive feature
Complete calculation steps22 (13–39)20 (3–36)1,878 (0.046)
Calculation steps EO12 (5–21)10 (1–21)1,690 (0.006)
Calculation steps EC10 (4–18)9 (2–17)2,036.5 (0.174)

* Statistical tests for group comparison: Mann-Whitney U test (Mann-Whitney U value). EC: eyes closed; EO: eyes open; HC: healthy controls; MSV3D: Mean angular Sway Velocity in 3D; pwMS: persons with multiple sclerosis