In memory of Antonia Fernández, mother of RF, who recently left us. You remain in the hearts of the daughter, son, granddaughters, and great-grandchildren.
Rafael Franco is the Editor-in-Chief of Exploration of Neuroprotective Therapy, but he had no involvement in the journal review process of this manuscript.
Watve M, Keskar Sardeshmukh A. “Vitaction” deficiency: a possible root cause for multiple lifestyle disorders including Alzheimer’s disease.Explor Neuroprot Ther. 2024;4:108–18. [DOI]
Carpenter KJ. The discovery of vitamin C.Ann Nutr Metab. 2012;61:259–64. [DOI] [PubMed]
Aykroyd WR. The vitamin B2 content of cereals and the supposed connection between human pellagra and deficiency of this vitamin.Biochem J. 1930;24:1479–88. [DOI] [PubMed] [PMC]
Guha BC. Vitamin B2 and pellagra: the etiology of pellagra.Br Med J. 1931;2:53–4. [DOI] [PubMed] [PMC]
Elvehjem CA. Early experiences with niacin; a retrospect.Nutr Rev. 1953;11:289–92. [DOI] [PubMed]
Williams RR. The Chemistry and Biological Significance of Thiamin.Science. 1938;87:559–63. [DOI] [PubMed]
Funk C. Studies on beri-beri: VII. Chemistry of the vitamine-fraction from yeast and rice-polishings.J Physiol. 1913;46:173–9. [DOI] [PubMed] [PMC]
Funk C. Studies on beri-beri: further facts concerning the chemistry of the vitamine-fraction from yeast.Br Med J. 1913;1:814. [DOI] [PubMed] [PMC]
Franco R, Serrano-Marín J. Can chronic therapeutic drug use by the elderly affect Alzheimer’s disease risk and rate of progression?Explor Neuroprot Ther. 2023;3:8–23. [DOI]
Ojha A, Watve M. Reduced blood to brain glucose transport as the cause for hyperglycemia: a model that resolves multiple anomalies in type 2 diabetes. Qeios. 2024. [DOI]
Ando S, Fujimoto T, Sudo M, Watanuki S, Hiraoka K, Takeda K, et al. The neuromodulatory role of dopamine in improved reaction time by acute cardiovascular exercise.J Physiol. 2024;602:461–84. [DOI] [PubMed]
Vega SR, Knicker A, Hollmann W, Bloch W, Strüder HK. Effect of resistance exercise on serum levels of growth factors in humans.Horm Metab Res. 2010;42:982–6. [DOI] [PubMed]
Kami K, Tajima F, Senba E. Exercise-induced hypoalgesia: potential mechanisms in animal models of neuropathic pain.Anat Sci Int. 2017;92:79–90. [DOI] [PubMed]
Castillo-Mariqueo L, Giménez-Llort L. Clasping, ledge-score coordination and early gait impairments as primary behavioural markers of functional impairment in Alzheimer’s disease.Behav Brain Res. 2022;435:114054. [DOI] [PubMed]
Meng Q, Lin M, Tzeng I. Relationship Between Exercise and Alzheimer’s Disease: A Narrative Literature Review.Front Neurosci. 2020;14:131. [DOI] [PubMed] [PMC]
Nabe-Nielsen K, Holtermann A, Gyntelberg F, Garde AH, Islamoska S, Prescott E, et al. The effect of occupational physical activity on dementia: Results from the Copenhagen Male Study.Scand J Med Sci Sports. 2021;31:446–55. [DOI] [PubMed]
Jaberi S, Fahnestock M. Mechanisms of the Beneficial Effects of Exercise on Brain-Derived Neurotrophic Factor Expression in Alzheimer’s Disease.Biomolecules. 2023;13:1577. [DOI] [PubMed] [PMC]
Zukowska-Grojec Z, Karwatowska-Prokopczuk E, Rose W, Rone J, Movafagh S, Ji H, et al. Neuropeptide Y: a novel angiogenic factor from the sympathetic nerves and endothelium.Circ Res. 1998;83:187–95. [DOI] [PubMed]
Jantaratnotai N, Ling A, Cheng J, Schwab C, McGeer PL, McLarnon JG. Upregulation and expression patterns of the angiogenic transcription factor ets-1 in Alzheimer’s disease brain.J Alzheimers Dis. 2013;37:367–77. [DOI] [PubMed]
Lopez-Lopez A, Labandeira CM, Labandeira-Garcia JL, Muñoz A. Rho kinase inhibitor fasudil reduces l-DOPA-induced dyskinesia in a rat model of Parkinson’s disease.Br J Pharmacol. 2020;177:5622–41. [DOI] [PubMed] [PMC]
Jefferies WA, Price KA, Biron KE, Fenninger F, Pfeifer CG, Dickstein DL. Adjusting the compass: new insights into the role of angiogenesis in Alzheimer’s disease.Alzheimers Res Ther. 2013;5:64. [DOI] [PubMed] [PMC]
Higginson AD, McNamara JM, Houston AI. Fatness and fitness: exposing the logic of evolutionary explanations for obesity.Proc Biol Sci. 2016;283:20152443. [DOI] [PubMed] [PMC]
Vakharia JD, Thaweethai T, Licht P, Wexler DJ, Delahanty LM. Psychological and Behavioral Predictors of Weight Loss in the Reach Ahead for Lifestyle and Health-Diabetes Lifestyle Intervention Cohort.J Acad Nutr Diet. 2023;123:1033–43.e1. [DOI] [PubMed] [PMC]
Chen G, Weiskirchen S, Weiskirchen R. Vitamin A: too good to be bad?Front Pharmacol. 2023;14:1186336. [DOI] [PubMed] [PMC]
Marcinowska-Suchowierska E, Kupisz-Urbańska M, Łukaszkiewicz J, Płudowski P, Jones G. Vitamin D Toxicity-A Clinical Perspective.Front Endocrinol (Lausanne). 2018;9:550. [DOI] [PubMed] [PMC]
Lorenzini J. Classification of Vitamins.Presse Medicale. 1927;35:166–7.
Combs GF Jr, McClung JP. The Vitamins: Fundamental Aspects in Nutrition and Health. Elsevier; 2017.
Snowdon D. Aging With Grace: The Nun Study and the Science of Old Age - How We Can All Live Longer, Healthier and More Vital Lives. Fourth Estate Paperbacks; 2002.
Butler SM, Ashford JW, Snowdon DA. Age, education, and changes in the Mini-Mental State Exam scores of older women: findings from the Nun Study.J Am Geriatr Soc. 1996;44:675–81. [DOI] [PubMed]