HCV RNA+ patients on SOWL before and after introduction of DAAs

IndicatorMeasure

Overall

2008–2019

P1, Years

2008–2013

P2, Years

2014–2019

Difference

P2 – P1

Mann-Whitney U test

Monte-Carlo-Significance (2-sided)

A) Listed on SOWL by requested organ
Any organSum32822999–130P = 0.004 (99% CI = 0.002 to 0.006)
Mean27.3338.1716.5–21.67
SD13.518.217.23
LiverSum28419787–110P = 0.004 (99% CI = 0.002 to 0.005)
Mean23.6732.8314.5–18.33
SD11.567.655.82
KidneySum382810–18P = 0.031 (99% CI = 0.027 to 0.036)
Mean3.174.671.67–3
SD2.381.861.86
B) Delisted from SOWL by reason
TransplantedSum21514174–67P = 0.010 (99% CI = 0.007 to 0.012)
Mean17.9223.512.33–11.17
SD7.684.425.96
Not transplantedSum28217–14P = 0.049 (99% CI = 0.043 to 0.054)
Mean4.673.51.17–2.33
SD2.272.431.47
DeceasedSum42339–24P < 0.001 (99% CI = 0 to 0.0005)
Mean3.55.51.5–4
SD2.541.761.22

CI: confidence interval