Table Info

Table 1.

Studies (n = 13) evaluating liver stiffness by VCTE and HCC occurrence in HBV patients. Composite model comprising VCTE

Author & year	Region	Virological status	Patients (n)	Mean age (years)	F-U months	HCC (n)	Prevalence (%)	Proposed cut-off (kPa)	AUROC	Sens (%)	Spec (%)	PPV	NPV	LR+	LR–
Jung et al., 2011 [13]	Korea	Mixed	1,130	50.2	31	57	5	8	-	-	-	-	-	-	-
Chon et al., 2012 [11]	Korea	Mixed	1,126	50.2	30.7	63	5.5	-	0.789	-	-	-	-	-	-
Kim et al., 2012 [14]	Korea	No therapy at baseline	128	52.5	27.8	14	11	≥ 19	0.722	61.1	86.2	-	-	4.36	0.45
Kim et al., 2013 [15]	Korea	Mixed	1,250	50	30.7	56	4.5	-	0.802	-	-	-	-	-	-
Wong et al., 2014 [16]	China	Mixed	1,555	46 ± 12	69	55	3.5	≥ 11	0.89	87.9		-	99.4	-	-
Kim et al., 2015 [17]	Korea	Mixed	2,876	46.1	48.9	52	1.8	≥ 13	-	-	-	-	-	-	-
Bihari et al., 2016 [18]	Asia	Mixed	964	38.6 ± 14.6	-	14	1.4	-	0.767*	-	-	-	-	-	-
Seo et al., 2016 [10]	Asia	No therapy at baseline	381	44.1 ± 12.3	48.1	34	8.9	-	0.745	-	-	-	-	-	-
Jeon et al., 2017 [19]	Korea	Mixed	540	51.5	54.1	81	15	≥ 13	0.598	-	-	-	-	-	-
Li et al., 2017 [20]	China	Viral suppression	1,200	40–59	-	156	13	≥ 9.7	-	-	-	-	-	-	-
Izumi et al., 2019 [21]	Japan	Mixed	377	-	27	23	6	≥ 6.2	0.79520	73.9	82.2	21.3	98	4.11	0.31
Wang et al., 2019 [12]	Taiwan, China	Viral suppression	257	52.6	45.6	27	10	≥ 21.5	0.636	55.6	64.2	-	-	1.5	0.68
Lee et al., 2021 [22]	Korea	Viral suppression	880	53.1	24	81	9	≥ 6.4	-	-	-	-	-	-	-

*: composite outcome; VCTE: vibration-controlled transient elastography

Supplementary materials

The supplementary materials for this article are available at: https://www.explorationpub.com/uploads/Article/file/100555_sup_1.pdf.

Declarations

Author contributions

AF: Investigation, Writing—original draft. MF: Conceptualization, Investigation, Writing—original draft, Writing—review & editing, Supervision. All authors read and approved the submitted version.

Conflicts of interest

The authors declare that they have no conflicts of interest.

Ethical approval

Not applicable.

Consent to participate

Not applicable.

Consent to publication

Not applicable.

Availability of data and materials

The primary data for this review were sourced online from databases listed in the methods.

Funding

Not applicable.

Copyright

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