Table Info

Table 2.

Studies (n = 13) evaluating liver stiffness by VCTE and HCC occurrence in patients with HCV

Author & year	Region	SVR	Patients (n)	Mean age (years)	F-U months	HCC (n)	Prevalence (%)	Proposed cut-off (kPa)	AUROC	Sens (%)	Spec (%)	PPV	NPV	LR+	LR–
Masuzaki et al., 2008 [29]	Japan	-	265	-	8	85	32	≥ 25	0.805	-	-	-	-	-	-
Masuzaki et al., 2009 [30]	Japan	No	866	62.2 ± 11.3	36	77	8.9	≥ 25	-	-	-	-	-	-	-
Wang et al., 2013 [27]	Taiwan, China	Mixed	198	53.0 ± 11.2	47.8	10	5	≥ 12	-	-	-	-	-	-	-
Calvaruso et al., 2013 [31]	Italy	No	233	-	42 ± 18	20	8.5	≥ 21	0.73	70	60	-	-	1.75	0.5
Feier et al., 2013 [32]	Romania	No	184	62.23	-	72	39	≥ 38.5	0.68	51.7	90.4	86.1	61.8	5.2	0.5
Narita et al.,2014 [33]	Japan	No	151	62	24	9	5.9	≥ 14	-	-	-	-	-	-	-
Wang et al., 2016 [34]	Taiwan, China	SVR	278	54.1	91.2	18	6.5	≥ 12	0.781	55.6	91.9	-	-	0.7	0.5
D’Ambrosio et al., 2018 [35]	Italy	No	404	63	36	24	6	≥ 30	-	-	-	-	-	-	-
Degasperi et al, 2019 [36]	Italy	No	546	64	25	28	5	≥ 30	-	-	-	-	-	-	-
Nakagomi et al., 2019 [28]	Japan	No	1,146	63	79.2	190	16.5	-	-	-	-	-	-	-	-
Pons et al., 2020 [37]	Spain	SVR	572	63.7	33.6	25	4	-	-	-	-	-	-	-	-
Izumi et al, 2019 [21]	Japan	Mixed	419	-	30	32	7.6	≥ 8	0.80592	84.4	63.3	16.1	98	2.3	0.25
Rinaldi et al., 2019 [38]	Italy	SVR	258	68	24	35	13.5	≥ 27.8	0.691	72	65	-	-	2.05	0.4

SVR: sustained virological response; VCTE: vibration-controlled transient elastography

Supplementary materials

The supplementary materials for this article are available at: https://www.explorationpub.com/uploads/Article/file/100555_sup_1.pdf.

Declarations

Author contributions

AF: Investigation, Writing—original draft. MF: Conceptualization, Investigation, Writing—original draft, Writing—review & editing, Supervision. All authors read and approved the submitted version.

Conflicts of interest

The authors declare that they have no conflicts of interest.

Ethical approval

Not applicable.

Consent to participate

Not applicable.

Consent to publication

Not applicable.

Availability of data and materials

The primary data for this review were sourced online from databases listed in the methods.

Funding

Not applicable.

Copyright

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