Active ingredients in traditional Chinese medicine that possess immunomodulatory properties and hepatoprotective effects, reducing transaminase activity
Category | Name | Source | Pathway and mechanism of action | Literature |
---|---|---|---|---|
Active ingredients of traditional Chinese medicine | Silymarin | Silybum marianum (L.) Gaertn. | Increase liver glycogen, catalase, and glutathione peroxidase activities. | [3] |
Glycyrrhizin | Glycyrrhiza uralensis Fisch. | Inhibiting the activation of NKT cells and Th17 cells, downregulating IL-17, and upregulating IL-25. | [12] | |
Baicalin | Scutellaria baicalensis Georgi. | Induction of Nrf2 accumulation, upregulation of IL-18, PCNA, and cyclinD1 expression, enhancing the proliferation ability of liver cells. | [13] |
Th17: T helper type 17; IL-17: interleukin-17
CL: Writing—review & editing, Investigation. CW: Investigation. XY: Writing—review & editing, Supervision.
The authors declare that they have no conflicts of interest.
Not applicable.
Not applicable.
Not applicable.
Not applicable.
Not applicable.
© The Author(s) 2024.