Active ingredients in traditional Chinese medicine that possess immunomodulatory properties and hepatoprotective effects, reducing transaminase activity

CategoryNameSourcePathway and mechanism of actionLiterature
Active ingredients of traditional Chinese medicineSilymarinSilybum marianum (L.) Gaertn.Increase liver glycogen, catalase, and glutathione peroxidase activities.[3]
GlycyrrhizinGlycyrrhiza uralensis Fisch.Inhibiting the activation of NKT cells and Th17 cells, downregulating IL-17, and upregulating IL-25.[12]
BaicalinScutellaria baicalensis Georgi.Induction of Nrf2 accumulation, upregulation of IL-18, PCNA, and cyclinD1 expression, enhancing the proliferation ability of liver cells.[13]

Th17: T helper type 17; IL-17: interleukin-17