Multivariate analyses for overall survival of patients with MSS
Factor
P
Exp (B)
95% CI min
95% CI max
Primary tumor(yes vs. no)
0.050
0.33
0.10
1.00
Ascites(yes vs. no)
< 0.001
0.20
0.08
0.49
Line of immunotherapy (I–II vs. III–IV)
0.004
0.24
0.09
0.63
NLR (< 1.8 vs. ≥ 1.8)
0.006
0.23
0.08
0.65
MSS: microsatellite stable; NLR: neutrophil-lymphocyte ratio
Declarations
Acknowledgments
Authors express their appreciation to Evdokimov V. I., Fedorinov D. S., and Tsaryova A. S. for their help in collecting data. Participating centers: N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia; Moscow Multidisciplinary Clinical Center “Kommunarka”, Moscow Healthcare Department; Branch “Oncology Center No. 1 of the City Clinical Hospital named after S. S. Yudin of the Moscow Department of Health”; A.S. Loginov Moscow Clinical Scientific Center, Moscow Healthcare Department; Moscow City Oncology Hospital No. 62, Moscow Healthcare Department.
Author contributions
AR: Investigation, Methodology, Writing—original draft. MF: Investigation, Methodology, Writing—review & editing, Formal analysis. DP, ML, LZ, DS, MV, IP, and NB: Writing—review & editing. AT: Conceptualization, Supervision, Writing—review & editing. All authors read and approved the submitted version.
Conflicts of interest
The authors declare that they have no conflicts of interest.
Ethical approval
The research proposal was submitted at the academic meeting and approved by the local ethics committee on 23.01.2021. The Local Committee of Scientific Research Ethics at N.N. Blokhin National Medical Research Center of Oncology was registered with the Federal Service for Supervision of Health and Social Development on 10.02.2006 (license number 01-3775/06).
Consent to participate
The Local Committee of Scientific Research Ethics at N.N. Blokhin National Medical Research Center of Oncology exempted informed consent to participate in this manuscript.
Consent to publication
Not applicable.
Availability of data and materials
Requests for accessing the datasets should be directed to [Alexey Tryakin, atryakin@gmail.com].
Open Exploration maintains a neutral stance on jurisdictional claims in published institutional affiliations and maps. All opinions expressed in this article are the personal views of the author(s) and do not represent the stance of the editorial team or the publisher.
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