Characteristics of study subjects
Parameters | Control group | Multiple sclerosis | P |
---|---|---|---|
N | 22 | 24 | Ns |
Sex, N (%) Female b | 16 (72.7%) | 16 (66.6%) | Ns |
Age in years a | 38.4 ± 14 | 35.5 ± 10 | Ns |
Disease duration in years a | Na | 15.9 ± 12.5 | - |
EDSS | |||
Mild, N (%) | Na | 17 (70.8%) | - |
Moderate, N (%) | Na | 4 (16.7%) | - |
Severe, N (%) | Na | 3 (12.5%) | - |
Disease course | |||
Relapsing-remitting, N (%) | Na | 20 (83.3%) | - |
Primary progressive, N (%) | Na | 4 (16.7%) | - |
a Values expressed in mean ± standard deviation, student’s t-test; b values expressed in percentage, χ2 test. Na: not applicable; Ns: non-significant (P > 0.05). Expanded disability status scale (EDSS) scores were categorized as mild, no to minimal disability (EDSS 0–2.5), moderate (EDSS 3–5), and severe (EDSS 5.5–10)
We would like to thank Editage (www.editage.com.br) for English language editing.
PHVD: Investigation, Data curation, Writing—original draft. RPS: Investigation. PPC: Investigation, Conceptualization. JANM: Investigation, Conceptualization. CMOV: Conceptualization, Validation, Writing—review & editing, Supervision.
The authors declare that they have no conflict of interest.
All procedures involving human participants performed in this study were in accordance with the ethical standards of the institutional and national research committee, were approved by Dr. Francisco das Chagas Lima and Silva Ethics Committee of Santa Casa Hospital of Belo Horizonte, Brazil (approval number 69385917.7.0000.5138), and complied with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.
The informed consent to participate in the study was obtained from all participants.
Not applicable.
Some datasets generated and analyzed in this study are not publicly available but are available from the corresponding author upon reasonable request.
This study was supported by CAPES (Coordenação de Aperfeiçoamento de Pessoal de Nível Superio), CNPq (Conselho Nacional de Desenvolvimento Científico) and FAPEMIG (Fundação de Amparo à Pesquisa do Estado de Minas Gerais). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
© The Author(s) 2024.