Table Info

Table 4.

Cortical regions with increasing rsEEG theta (P ≤ 0.05) by age groups

GDS stages for age groups	Absolute theta	Relative theta
Group 1, n = 14
GDS 1, n = 0	-	-
GDS 2, n = 3	-	Left lateral central, left temporal, right lateral central
GDS 3, n = 3	-	-
GDS 4, n = 2	-	Left & right frontal pole, left & right frontal, left & right lateral central, left & right parietal, left & right lateral frontal, left temporal, left & right lateral temporal, frontal-central midline
GDS 5, n = 0	-	-
GDS 6, n = 6	-	Left & right frontal pole, left & right frontal, left & right lateral central, left & right parietal, left & right lateral frontal, left temporal, left & right lateral temporal, frontal-central midline
GDS 7, n = 0	-	-
Group 2, n = 13
GDS 1, n = 1	-	-
GDS 2, n = 3	-	-
GDS 3, n = 1	-	-
GDS 4, n = 2	-	-
GDS 5, n = 1	Left & right frontal, frontal midline	Left & right frontal pole, left & right frontal, right lateral central, left & right lateral frontal, left temporal, right lateral temporal, frontal midline
GDS 6, n = 4	-	-
GDS 7, n = 1	Left & right frontal pole, left & right frontal, left & right lateral central, left & right parietal, left & right occipital, left & right lateral frontal, left temporal, left lateral temporal, frontal-central-parietal midline	Entire head (all cortical regions)
Group 3, n = 14
GDS 1, n = 1	Left & right frontal, left & right lateral central, left & right parietal	-
GDS 2, n = 0	-	-
GDS 3, n = 4	-	-
GDS 4, n = 2	Left & right frontal, left & right lateral central, left & right parietal, left lateral frontal, left temporal, right lateral temporal, central-parietal midline	Left temporal
GDS 5, n = 6	Left & right frontal pole, left & right frontal, left & right lateral central, left & right parietal, left & right occipital, left & right lateral frontal, left temporal, left & right lateral temporal, frontal-central-parietal midline	Left & right frontal pole, left & right frontal, left lateral central, left & right lateral frontal, left & right temporal, left & right lateral temporal, frontal-central midline
GDS 6, n = 0	-	-
GDS 7, n = 1	-	-
Group 4, n = 13
GDS 1, n = 0	-	-
GDS 2, n = 2	-	-
GDS 3, n = 5	-	-
GDS 4, n = 5	-	-
GDS 5, n = 1	Left temporal	Right lateral frontal, left temporal
GDS 6, n = 0	-	-
GDS 7, n = 0	-	-

Italicized means non-converters. Age groups: Group 1 = age 58.26–66.40; Group 2 = age 66.48–73.58; Group 3 = age 73.79–80.07; Group 4 = age 80.82–89.51. GDS: Global Deterioration Scale; rsEEG: resting-state electroencephalogram. -: no data

Declarations

Acknowledgments

The author acknowledges contextual support from Dr. Leslie S. Prichep (Chief Scientific Officer, BrainScope), Dr. Toni Tripp-Reimer, deceased in December 13, 2021 (The University of Iowa College of Nursing), and Dr. Faye A. Gary (Professor, Case Western Reserve University, FPB School of Nursing).

Author contributions

ECH: Conceptualization, Data curation, Writing—original draft, Writing—review & editing, Visualization.

Conflicts of interest

The author of this article does not have any conflicts of interest to disclose.

Ethical approval

This present study, secondary analysis, had ethical approval and received exemption status from the New York University Institutional Review Board and the New York University School of Medicine Institutional Review Board. The ethical approval and exemption status was on April 15, 2002, with the date serving as the ethical approval number.

Consent to participate

This secondary analysis had ethical approval for informed consent exemption by the New York University Institutional Review Board and New York University School of Medicine Institutional Review Board.

Consent to publication

Not applicable.

Availability of data and materials

The datasets for this manuscript are not publicly available because this option for data sharing was not included in the IRB applications or ethically approved by New York University and New York University School of Medicine. Request for accessing the datasets should be directed to Dr. Leslie S. Prichep (leslie.prichep@brainscope.com).

Funding

Funded by the Substance Abuse and Mental Health Services Administration Minority Fellowship Program [2 T06 SM 151555] at the American Nurses Association and the Brain Research Laboratories, New York University School of Medicine. The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Copyright

Publisher’s note

Open Exploration maintains a neutral stance on jurisdictional claims in published institutional affiliations and maps. All opinions expressed in this article are the personal views of the author(s) and do not represent the stance of the editorial team or the publisher.

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