Comparison of epidemiologic and clinical characteristics of PDB and PsA
Characteristics | PsA | PDB |
---|---|---|
Age of onset, years | > 45 | > 50 |
Gender | F = M | F = M |
Familial history | Positive | Positive |
Vascular calcification | Is present | Is present |
Involvement of weight—bearing bony architecture | Lower extremity enthesitis (obesity) | Lower-extremities (long-bones) |
Pelvis | Pelvis | |
Axial spondylitis | Axial skeleton | |
Bone ALP | ↑↑ | ↑↑ |
CD association | Yes | Possibly |
OCLs morphology | Hypermultinucleated | Hypermultinucleated |
Oxidative stress | ↑ | ↑ |
Tissue vascularity | ↑↑ | ↑↑ |
Pattern of bone involvement | Asymmetric | Asymmetric |
Skipping non-marginal- syndesmophytes | Not crossing bone boundaries | |
Deep Koebner phenomenon | Confirmed | ? |
Daily trauma-related sites | DIP joints Ray distribution Dominant-hand thumbnail Obesity | Skull |
Environmental factors | Streptococcus/Drugs/Stress | Measles virus |
Prevalence | Increased | Decreased |
F: female; M: male; ↑: elevated; ↑↑: significantly elevated; ?: undetermined
I would like to express my gratitude to my wife, Mrs. Dr. Batool Dadkhah for her intellectual assistances.
FS: Conceptualization, Investigation, Writing—original draft, Writing—review & editing. The author read and approved the submitted version.
The author declares that there is no conflicts of interest.
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All required data are included in the manuscript.
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© The Author(s) 2024.