Table Info

Table 2.

Proposed list of quality standards and indicators for CPPD

Quality aspects		Quality standards
1	Organization	Time from referral to rheumatologist (< 1 week) Time from referral to diagnosis (work-up < 2 months)
2	Treatment	Monitoring disease activity/use of scores (VAS, RAPID-3) Disease control/treatment escalation (out of indication!)
3	Management	Education and self-management (shortly after diagnosis) Rapid access (flare or possibly drug-related adverse event) Review by rheumatologist (at least annually if in remission)

VAS: visual analogue scale; RAPID-3: Routine Assessment of Patient Index Data 3

Declarations

Author contributions

MS: Conceptualization, Investigation, Writing—original draft, Writing—review & editing, Supervision. JDP: Investigation, Writing—review & editing. Both authors read and approved the submitted version.

Conflicts of interest

The authors declare that they have no conflicts of interest.

Ethical approval

Not applicable.

Consent to participate

Not applicable.

Consent to publication

Not applicable.

Availability of data and materials

Not applicable.

Funding

Not applicable.

Copyright

References

Cipolletta E, Francioso F, Smerilli G, Di Battista J, Filippucci E. Ultrasound reveals a high prevalence of CPPD in consecutive patients with knee pain. Clin Rheumatol. 2024;43:435−41. [DOI] [PubMed]

Zhang W, Doherty M, Bardin T, Barskova V, Guerne PA, Jansen TL, et al. European League Against Rheumatism recommendations for calcium pyrophosphate deposition. Part I: terminology and diagnosis. Ann Rheum Dis. 2011;70:563−70. [DOI] [PubMed]

Guo SY, Lee CA, Wise BL. Chondrocalcinosis and Osteoarthritis: A Literature Review. Eur J Rheumatol. 2024;11:S15−20. [DOI] [PubMed]

Ferrone C, Andracco R, Cimmino MA. Calcium pyrophosphate deposition disease: clinical manifestations. Reumatismo. 2012;63:246−52. [PubMed]

Masuda I, Ishikawa K. Clinical features of pseudogout attack. A survey of 50 cases. Clin Orthop Relat Res. 1988;229:173−81. [PubMed]

Pallua J, Schirmer M. Identification of Five Quality Needs for Rheumatology (Text Analysis and Literature Review). Front Med (Lausanne). 2021;8:757102. [DOI] [PubMed] [PMC]

Abhishek A, Tedeschi SK, Pascart T, Latourte A, Dalbeth N, Neogi T, et al. The 2023 ACR/EULAR Classification Criteria for Calcium Pyrophosphate Deposition Disease. Arthritis Rheumatol. 2023;75:1703−13. [DOI] [PubMed] [PMC]

Atxotegi-Saenz de Buruaga J, Perez-Herrero N, Perez-Herrero N, Vazquez-Puente C, Modesto-Caballero MdC, Perez-Ruiz F. Association of mutations in hemochromatosis genes with clinical severity of calcium pyrophosphate arthritis. Explor Musculoskeletal Dis. 2023;1:186−93. [DOI]

Kellgren JH, Lawrence JS. Radiological assessment of osteo-arthrosis. Ann Rheum Dis. 1957;16:494−502. [DOI] [PubMed] [PMC]

10.

Felson DT, Anderson JJ, Naimark A, Kannel W, Meenan RF. The prevalence of chondrocalcinosis in the elderly and its association with knee osteoarthritis: the Framingham Study. J Rheumatol. 1989;16:1241−5. [PubMed]

11.

Doherty M, Watt I, Dieppe PA. Localised chondrocalcinosis in post-meniscectomy knees. Lancet. 1982;1:1207−10. [DOI] [PubMed]

12.

Richette P, Ayoub G, Lahalle S, Vicaut E, Badran AM, Joly F, et al. Hypomagnesemia associated with chondrocalcinosis: a cross-sectional study. Arthritis Rheum. 2007;57:1496−501. [DOI] [PubMed]

13.

Alizadeh BZ, Njajou OT, Hazes JMW, Hofman A, Slagboom PE, Pols HAP, et al. The H63D variant in the HFE gene predisposes to arthralgia, chondrocalcinosis and osteoarthritis. Ann Rheum Dis. 2007;66:1436−42. [DOI] [PubMed] [PMC]

14.

Abhishek A, Doherty M. Pathophysiology of articular chondrocalcinosis−role of ANKH. Nat Rev Rheumatol. 2011;7:96−104. [DOI] [PubMed]

15.

Tsui FWL. Genetics and mechanisms of crystal deposition in calcium pyrophosphate deposition disease. Curr Rheumatol Rep. 2012;14:155−60. [DOI] [PubMed]

16.

Parperis K, Papachristodoulou E, Kakoullis L, Rosenthal AK. Management of calcium pyrophosphate crystal deposition disease: A systematic review. Semin Arthritis Rheum. 2021;51:84−94. [DOI] [PubMed]

17.

Andrés M, Sivera F, Pascual E. Therapy for CPPD: Options and Evidence. Curr Rheumatol Rep. 2018;20:31. [DOI] [PubMed]

18.

Maravic M, Ea H. Hospital burden of gout, pseudogout and other crystal arthropathies in France. Joint Bone Spine. 2015;82:326–9. [DOI] [PubMed]

19.

Whelan MG, Hayashi K, Altwies H, Tedeschi SK. Patient-Reported Outcomes in Calcium Pyrophosphate Deposition Disease Compared to Gout and Osteoarthritis. J Rheumatol. 2023;50:1058–62. [DOI] [PubMed]

20.

Bech B, Primdahl J, Tubergen Av, Voshaar M, Zangi HA, Barbosa L, et al. 2018 update of the EULAR recommendations for the role of the nurse in the management of chronic inflammatory arthritis. Ann Rheum Dis. 2020;79:61–8. [DOI] [PubMed]

21.

Donabedian A. The quality of care. How can it be assessed? JAMA. 1988;260:1743–8. [DOI] [PubMed]

22.

Meyer GS, Massagli MP. The forgotten component of the quality triad: can we still learn something from “structure”? Jt Comm J Qual Improv. 2001;27:484–93. [DOI] [PubMed]

23.

Glickman SW, Baggett KA, Krubert CG, Peterson ED, Schulman KA. Promoting quality: the health-care organization from a management perspective. Int J Qual Health Care. 2007;19:341–8. [DOI] [PubMed]

24.

Kiltz U, Landewé RBM, Heijde Dvd, Rudwaleit M, Weisman MH, Akkoc N, et al. Development of ASAS quality standards to improve the quality of health and care services for patients with axial spondyloarthritis. Ann Rheum Dis. 2020;79:193–201. [DOI] [PubMed] [PMC]

25.

Woess C, Huck CW, Badzoka J, Kappacher C, Arora R, Lindtner RA, et al. Raman spectroscopy for postmortem interval estimation of human skeletal remains: A scoping review. J Biophotonics. 2023;16:e202300189. [DOI] [PubMed]

26.

Cheng X, Haggins DG, York RH, Yeni YN, Akkus O. Analysis of crystals leading to joint arthropathies by Raman spectroscopy: comparison with compensated polarized imaging. Appl Spectrosc. 2009;63:381–6. [DOI] [PubMed]

27.

Wu Y, Chen K, Terkeltaub R. Systematic review and quality analysis of emerging diagnostic measures for calcium pyrophosphate crystal deposition disease. RMD Open. 2016;2:e000339. [DOI] [PubMed] [PMC]

28.

Rutsch F, Terkeltaub R. Parallels between arterial and cartilage calcification: what understanding artery calcification can teach us about chondrocalcinosis. Curr Opin Rheumatol. 2003;15:302–10. [DOI] [PubMed]