Table Info

Table 4.

List of compounds with the highest results in cell line HEK293T-ACE2 [20]

Name of chemical compound	EC₅₀ (μmol/L)	CC₅₀ (μmol/L)	SI
Aloperine	0.28	> 50	> 176.87
Berbamine	1.28	> 50	> 38.94
Cepharanthine	0.32	> 50	> 158.58
Dauricine	1.43	> 50	> 34.99
Fangchinoline	0.94	> 50	> 53.39
Hernandezine	0.11	> 50	> 448.83
Isofangchinoline	1.11	> 50	> 45
Isoliensinine	0.923	> 50	> 54.17
Liensinine	1	> 50	> 49.8
Neferine	0.95	> 50	> 52.87
Tetrandrine	0.9	> 50	> 55.8

EC₅₀: half maximal effective concentration; CC₅₀: half cytotoxic concentration; SI: selectivity index

Supplementary materials

The supplementary material for this article is available at: https://www.explorationpub.com/uploads/Article/file/100817_sup_1.pdf.

Declarations

Author contributions

AK: Data curation, Visualization, Writing—original draft. NI: Data curation, Writing—original draft. IG and VP: Conceptualization, Supervision.

Conflicts of interest

The authors declare that they have no conflicts of interest.

Ethical approval

Not applicable.

Consent to participate

Not applicable.

Consent to publication

Not applicable.

Availability of data and materials

Not applicable.

Funding

The study is performed in the framework of the Program for Basic Research in the Russian Federation for a long-term period (2021–2030) project No. [121102900156-6]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Copyright

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