Table Info

Table 1.

Summary of platforms for tumor diagnosis and treatment with representative electrospun SFs

Application	Platforms	Method	Cell models	Mechanism of action	References
CTC capture	Fe₃O₄@PEI/PVA-Apt SFs	Homogenization treatment	MCF-7 cells	DNA Apt-based ligand-receptor binding to capture breast cancer cells in vitro	[23]
Tumor therapy	PDA-PLA SFs	Cutting and filtering	B16F10/T cells	Immunotherapy of melanoma	[10]
	Coumarin-PELA containing fiber rods	Ultrasonication treatment	4T1 and RAW 264.7	Chemotherapy of breast cancer	[36]
	DOX@LDH/α-TOS/PLGA SFs	Homogenization treatment	MCF-7/ADR cells	Chemotherapy of breast cancer cells in vitro	[39]
Tumor theranostics	DOX@PLGA-PEI-Gd/Apt	Homogenization treatment	4T1 tumor cells	Chemotherapy and MR imaging of breast cancer	[40]
Tumor theranostics	DOX-PLGA-PEI-DTPA-Gd/HA fiber microspheres	Homogenization treatment	4T1 tumor cells	Chemotherapy and MR imaging of breast cancer	[41]

Apt: aptamer; DOX: doxorubicin; DTPA: diethylenetriaminepentaacetic dianhydride; Gd: gadolinium; HA: hyaluronic acid; LDH: layered double hydroxide; MR: magnetic resonance; PDA: polydopamine; PEI: polyethylenimine; PELA: polyethylene glycol PLA; PVA: polyvinyl alcohol; α-TOS: α-tocopheryl succinate

Declarations

Author contributions

YH: Software, Writing—original draft. MZ: Writing—original draft. MS: Supervision, Resources, Project administration, Writing—review & editing. LZ: Writing—review & editing. XS: Supervision, Resources, Funding acquisition, Project administration, Writing—review & editing.

Conflicts of interest

The authors declare that they have no conflicts of interest.

Ethical approval

Not applicable.

Consent to participate

Not applicable.

Consent to publication

Not applicable.

Availability of data and materials

Not applicable.

Funding

This study is financially supported by the National Natural Science Foundation of China [52350710203]; the Science and Technology Commission of Shanghai Municipality [23520712500, 21490711500, 20DZ2254900]; the Shanghai Education Commission through the Shanghai Leading Talents Program; and the 111 Project [BP0719035]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Copyright

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