Histone deacetylases (HDACs) inhibitors
Drug | Model and mechanisms | Structure | Author | Reference |
---|---|---|---|---|
TMP195 | HDAC9 inhibition (hyperlipidemic mice) | Asare et al. (2020) | [163] | |
RGFP966 | HDAC3 inhibition (ApoE-/- mice) | Chen et al. (2021) | [164] | |
MC1568 | HDAC9 inhibition (ex vivo genetic knockout HDAC9 endothelial cells) | Lecce et al. | [165] | |
Sodium valproate | HDAC9 inhibition (human patients) | Brookes et al. (2018) | [166] |
We thank all members of the Department of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, and the National Natural Sciences Foundation of China for their support.
SCW: Writing—original draft. XMJ: Conceptualization, Investigation, Writing—review & editing. MX: Conceptualization, Investigation, Writing—review & editing, Funding acquisition.
The authors declare that they have no conflicts of interest.
Not applicable.
Not applicable.
Not applicable.
Not applicable.
This work is supported by the National Natural Science Foundation of China [82373870]. The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
© The Author(s) 2024.