Types of vaccines | Contents |
---|---|
Leishmanization | Live and virulent L. major or L. tropica |
Killed vaccines | Killed Leishmania species |
Live genetically modified vaccines (avirulent) | BT1 (biopterin transporter 1) |
Ldp27 (L. donovani amastigote specific protein p27) | |
HSP70-II nul (heat-schok protein) | |
KHARON1 | |
Cen (centrin) | |
Recombinant and subunit vaccines | Recombinant LEISH-F1, LIESH-F2 and LEISH-F3 |
LdA2, Ldp27, eIF-2, NH (nucleoside hydrolase), CPA (cysteine protease A), CPB, SMT (sterol 24-c-methyltransferase), H1 (histone-1), HSP, LACK | |
Sand fly saliva antigens: LJM19, LJL143, and PdSP15 | |
DNA vaccines | A2, LACK, TSA + LmSTI1, gp63 (glycoprotein 63), KMP-11 (kinetoplastid membrane protein 11), CPB, NH36, LeIF, gp63 + HS |
Semian adenovirus expressing NH and SMT | |
Live non-pathogenic vaccines | Avirulent Leishmania tarentolae |
I acknowledge the esteemed faculty and researchers at Bharati Vidyapeeth (Deemed to be University) Poona College of Pharmacy, Pune for their valuable contributions and support in the development of this review article. Their expertise and guidance have been instrumental in shaping the content and insights presented in this work. I extend my sincere gratitude to the institution for providing a conducive academic environment that fosters research excellence and innovation.
TM: Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing—original draft, Writing—review & editing. DK and DB: Formal analysis, Project administration, Supervision, Visualization, Writing—review & editing.
The authors declare that they have no conflicts of interest.
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© The Author(s) 2024.