Calculated IC50 (µM) of cationic bacteriochlorins for human fibroblasts WI-38 without irradiation and with irradiation of 12 J/cm2
| Photosensitizer | IC50 (µM) | |||
|---|---|---|---|---|
| Sensitization time | 30 min | 60 min | ||
| Light dose | 0 | 12 J/cm2 | 0 | 12 J/cm2 |
| BCl-5 | n | 9.55 | 65.0 | 11.65 |
| BCl-6 | n | 4.95 | n | 3.40 |
| BCl-7 | n | 4.50 | n | 4.20 |
n: not achieved
IT: Conceptualization, Investigation, Writing—original draft, Writing—review & editing. YZ and ET: Investigation, Methodology, Formal analysis. EM: Investigation, Writing—review & editing. AB and NS: Investigation, Formal analysis. VZ and MB: Methodology, Writing—review & editing, Validation. YR: Writing—review & editing. All authors read and approved the submitted version.
The authors declare that they have no conflicts of interest.
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The raw data supporting the conclusions of this manuscript will be made available by the authors, without undue reservation, to any qualified researcher.
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© The Author(s) 2024.