Advantages and disadvantages of peptides compared to other biomolecules [20, 29, 80]

CategoryPeptides vs small moleculesPeptides vs biomolecules
Disadvantages
  • Stability

  • Bioavailability

  • Membrane penetration

  • Stability and delivery for oral administration

  • Cost of production and sales

  • Stability

  • Bioavailability

  • Delivery

Advantages
  • Specificity

  • Safety

  • Clearance

  • Low possibility of generating resistance

  • Membrane permeability

  • Low cost in research and production

  • Intracellular targets

  • Low immunogenicity