Table Info

Table 1.

Compilation of ten years (2013–2023) of published studies concerning microbial biotransformations conducted by biofilms to produce high-value molecules

Group	Strain	Parental molecule(s)	Daughter molecule(s)	Use	Scaffold	Reference
Fungi	Candida viswanathii NBRC10321	Citronellal	Citronellic acid	Ingredient used in perfumes	Microspheres of PMMA	[60]
	Cunninghamella echinulata ATCC9244	Hesperetin	Hesperetin 7-O-glycoside	Arome of sweet orange	Stainless steel wool	[61]
	Cunninghamella echinulata ATCC9244	LQFM-021	N-glycosylated LQFM-021	Phosphodiesterase-3 inhibitor	Stainless steel mesh	[62]
	Cunninghamella elegans DSM1908	Diclofenac	4’-Hydroxydiclofenac	Cox-2 inhibitor	Stainless steel springs	[63]
	Cunninghamella elegans DSM1908	Diclofenac	4’-Hydroxydiclofenac	Cox-2 inhibitor	Stainless steel mesh	[57]
	Cunninghamella elegans DSM1908	Flurbiprofen	4-Hydroxyflurbiprofen	Standart for purity assays	Stainless steel springs	[64]
	Lasiodiplodia (Botryodiplodia) theobromae 1368	(+)-Valencene	(+)-Nootkatone	Arome of grapefruit	Permeable silicon rubber	[65]
	Mucor circinelloides URM4182	Babassu oil lipides	Ethyl esters (various)	Diverse applications	Polyurethane foams	[66]
	Pichia kluyveri NBRC1165	Citronellol	Citronellyl acetate	Mosquito repellent	Microspheres of PMMA	[60]
	Yarrowia lipolytica W29 (ATCC 20460)	Methylricinoleate	3-Hydroxy-γ-decalactone	Aromatic compound	Groupons of PMMA	[67]
Bacteria	Lactobacillus brevis RK03	Monosodium glutamate	γ-Aminobutyric acid (GABA)	Anti-seizure and anti-anxiety drug	Groupons of HEMA/PEGDA	[68]
	Bacillus subtilis BS-7	Ferulic acid	Vanilin	Aromatic compound	Carbon fiber textiles	[69]
	Bacillus subtilis BS-7 S	Ferulic acid	Vanilin	Aromatic compound	Active carbon fiber	[70]
	Escherichia coli BL21	5-Nitrononane-2,8-dione	(R)-syn/anti-hydroketone	Diverse applications	PDMS	[71]
	Escherichia coli BL21(DE3)	Indole	Tryptophan	Amino acid	Cellulose sponge	[72]
	Escherichia coli MG1655	5-Haloindole	5-Halotryptophan	Pharmaceutical intermediary	Glass slides with poly-L-lysine	[73]
	Pseudomonas diminuta ATCC19146	Ethylene glycol	Glycolic acid	Anti-aging agent	Stainless steel structured packing	[74]
	Pseudomonas putida GS1	(R)-(+)-Limonene	(R)-(+)-Perillic acid	Antineoplastic agent	Silicon membrane	[75]
	Pseudomonas taiwanensis VLB120 B83 T7	Glucose	(S)-3-Hydroxyisobutyric acid	Intermediate in the metabolism of valine	Silicon tubing	[75]
	Rhodococcus hoagii NBRC3730	2-Octanol	2-Octanone	Ingredient used in perfumes	Microspheres of PMMA	[76]
Associations	Synechocystis sp. PCC 6803 plus	Cyclohexane	Cyclohexanol	Plasticizer agent	Borosilicate glass	[77]
Associations	Pseudomonas sp. VLB120	Cyclohexane	Cyclohexanol	Plasticizer agent	Borosilicate glass	[78]

LQFM-021: 5-(1-(3-Fluorophenyl)-1H-pyrazol-4-yl)-2H-tetrazole; PMMA: methyl-polymethacrylate; HEMA/PEGDA: hydroxyethyl methacrylate/polyethylene glycol diacrylate; PDMS: polydimethylsiloxane

Declarations

Acknowledgments

NSO, RCPSR, and RCP had scholarships from the Coordination for the Improvement of Higher Education Personnel (CAPES-Brazil financial code 001). MGCP had a scholarship from the National Council for Scientific and Technological Development (CNPq-Brazil).

Author contributions

NSdO: Data curation, Writing—original draft. RCPdSR, RCdP, MGdCP, and RTR: Data curation. LFB and EARR: Writing—review & editing.

Conflicts of interest

The authors declare that they have no conflicts of interest.

Ethical approval

Not applicable.

Consent to participate

Not applicable.

Consent to publication

Not applicable.

Availability of data and materials

Not applicable.

Funding

Not applicable.

Copyright

Publisher’s note

Open Exploration maintains a neutral stance on jurisdictional claims in published institutional affiliations and maps. All opinions expressed in this article are the personal views of the author(s) and do not represent the stance of the editorial team or the publisher.

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