Antimicrobial drugs with their mechanism of action

S. No.Antimicrobial drugsUseTarget microbeReferences
1Antisense phosphorothioate oligonucleotideHelps fluoroquinolone-resistant Escherichia coli regain antibiotic sensitivity by targeting acrB geneEscherichia coli[14]
2AmikacinEffective against bacterial infectionsMycobacterium and Pseudomonas aeruginosa[15]
3Vancomycin and linezolidUsed to treat complex skin and soft-tissue infections brought on by methicillin-resistant Staphylococcus aureus (MRSA) as well as nosocomial pneumoniaStaphylococcus aureus[16]
4Penicillin G procaine and pirlimycinUsed for treating mastitis in lactating cowsMycoplasma spp. and Streptococcus agalactiae[17]
5Silica-based biomaterials loaded with ferulic acidUsed in bone tissue engineering to promote bone graft healing and stop bacterial infectionsStaphylococcus aureus and E. coli[18]
6Non-canonical amino acids (NCAAs)Plays a role in designing antimicrobial peptides to combat multidrug-resistant bacteriaGram-positive and Gram-negative bacteria[19]
7CiprofloxacinThis medication is a component of a new thermo-responsive hydrogel formulation intended for drug-eluting usesGram-negative bacteria[20]
8Taromycin A and Gassericin AExhibit binding mechanism by interacting with Lys 234Antibiotic resistant bacteria that produce TEM-1 β-lactamases[21]