Table Info

Table 1.

Characteristics of psoriasis and contact dermatitis for differential diagnosis

Characteristics	Psoriasis	Contact dermatitis
Sites involved	Knees, elbows, scalps, palm and sole, all body	Sites in contact with irritants or allergens
Symptoms	Generally none	Burning in irritant form, itching in allergic form
Signs	Solitary or multiple erythematous plaques with characteristic adherent silvery white scales, Koebner phenomenon	Erythema, edema, papule and vesicles, fissures in irritant form; hyperkeratosis in chronic form
Histology
Parakeratosis	Moderate or strong, confluent; para-/ortho-keratosis	Mild and in multiple foci
Acanthosis	Regular	More irregular
Granular layer	Thinner	Normal
Capillaries in the upper dermis	Tortuous or dilatate	Horizontal
Lymphocytic exocytosis in epidermis	No (less likely)	Yes
Edema of papillary dermis	No (less likely)	Yes
Spongiosis	More frequent	Less frequent
Munro microabscesses	Yes	No
Prevention	Not available	Avoidance of contact with irritants or sensitizing agents

Declarations

Author contributions

EC and M Perlato equally contributed to: Conceptualization, Data curation, Project administration, Supervision, Writing—original draft, Writing—review & editing. EN, MC, and OR: Conceptualization, Writing—original draft. L Salvati, EDA, AR, DP, FA, RM, SM, NS, MT, LDB, M Passante, MDP, ADM, LP, LA, RC, IM, IT, MEC, SF, RG, AZ, EB, AB, DB, MN, MB, TDP, FG, CP, KH, FLF, IZ, ST, SG, CF, and L Stingeni: Writing—original draft. All authors read and approved the final version of the manuscript.

Conflicts of interest

The authors declare that they have no conflicts of interest.

Ethical approval

Ethical approval was waived by the “AREA VASTA CENTRO” Ethics Committee since this is a scientific literature review.

Consent to participate

The informed consent to participate in the study was obtained from relevant participants or the parents of relevant participants (under 16 years old).

Consent to publication

The informed consent to publication was obtained from relevant participants or the parents of relevant participants (under 16 years old).

Availability of data and materials

Not applicable.

Funding

Not applicable.

Copyright

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