Major features:

• Typical morphology and distribution: flexural lichenification or linearity in adults. Facial and extensor involvement in infants and children

• Chronic or chronically relapsing dermatitis

• Personal or family history of atopy (asthma, allergic rhinitis, atopic dermatitis)

Minor features:

• Xerosis

• Ichthyosis/palmar hyperlinearity/keratosis pilaris

• Immediate (type 1) skin test reactivity

• Elevated serum IgE

• Early age of onset

• Tendency towards cutaneous infections

• Tendency towards nonspecific hand or foot dermatitis

• Nipple eczema

• Cheilitis

• Recurrent conjunctivitis

• Dennie-Morgan infraorbital fold

• Keratoconus

• Anterior subcapsular cataracts

• Orbital darkening

• Facial pallor/erythema

• Pityriasis alba

• Anterior neck folds

• Itch when sweating

• Intolerance to wool and lipid solvents

• Food intolerance

• Course influenced by environmental/emotional factors

• White dermographism/delayed blanch

Major feature:

• Itchy skin condition

Minor features:

• History of asthma/hay fever

• History of generalised dry skin

• Onset of rash under the age of 2 years

• Visible flexural dermatitis

Diagnosis: major plus three or more of the minor features

Major features:

• Pruritus

• Typical morphology and distribution

• Chronic or chronically relapsing course

Diagnosis:

All above features must be present for more than 2 months in infancy and more than 6 months in childhood, adolescence, and adulthood.

Major feature:

• Symmetrical eczema (dermatitis) for more than 6 months

Minor features:

• Personal and/or family history of atopic diseases

• Elevated total serum IgE level and/or positive allergen specific IgE and/or eosinophilia

Diagnosis: major plus one or more of the minor features