Table Info

Table 5.

RTX therapy in patients with EGPA

Reference	Study design	Number of patients	Dose and route of administration	Results
Cartin-Ceba et al. [89], 2011	Prospective open-label pilot study	3	375 mg/m² every 4 weeks	All patients achieved renal remission
Thiel et al. [85], 2013	Single-center cohort of patients	9	No recorded	CS reduction BVAS reduction C-reactive protein normalized Reduction in blood eosinophil counts No relapses had been recorded
Mohammad et al. [83], 2016	Cohort of patients	41	375 mg/m² every 4 weeks (n = 10) 2 doses 1,000 mg (n = 30)	34% Of the patients achieved remission CS reduction in all patients ANCA-positivity at baseline was associated with a higher remission rate at 12 months No differences in eosinophil counts
Teixera et al. [87], 2019	Cohort of patients	69	-	No differences in treatment response according to ANCA-status CS reductions No changes in blood eosinophil counts

-: blank cell

Declarations

Author contributions

ACH: Conceptualization, Investigation, Writing—original draft, Writing—review & editing. CP: Conceptualization, Investigation, Visualization, Writing—review & editing. GP: Validation, Writing—review & editing, Supervision. All authors read and approved the submitted version.

Conflicts of interest

The authors declare that they have no conflicts of interest.

Ethical approval

Not applicable.

Consent to participate

Not applicable.

Consent to publication

Not applicable.

Availability of data and materials

Not applicable.

Funding

Not applicable.

Copyright

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