* Derived from a Draper-Lin reduced composite design (16 random orthogonal runs and ** 2 center points). X1: ethanol concentration (%); X2: emulsifier (%); X3: extraction time (min); X4: g PDCF/mL solvent; ABTS: radical scavenging activity. In each column samples with different letters are statistically different at the level of alpha = 0.05. Equations at the bottom of the table are those of the fitted model based on the regression coefficients for the different responses
This research was supported by Secretaría de Ciencia y Tecnología (Universidad Nacional de Córdoba) and Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET). We would like to thank Fernanda Quiroga for her technical help.
Author contributions
MA: Data aquisition, Formal analysis, Methodology, Writing—original draft. CA: Methodology, Writing—original draft. DD and LM: Data acquisition, Methodology. AA: Conceptualization, Study design, Funding acquisition. RB: Conceptualization, Study design, Formal analysis, Funding acquisition, Writing—review & editing.
Conflicts of interest
The authors declare that they have no conflicts of interest.
Ethical approval
Not applicable.
Consent to participate
Not applicable.
Consent to publication
Not applicable.
Availability of data and materials
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Funding
This research was supported by Secretaría de Ciencia y Tecnología (Universidad Nacional de Córdoba) and Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Sandoval-Oliveros MR, Paredes-López O. Isolation and characterization of proteins from chia seeds (Salvia hispanica L.).J Agric Food Chem. 2013;61:193–201. [DOI] [PubMed]
Martínez ML, Marín MA, Salgado Faller CM, Revol J, Penci MC, Ribotta PD. Chia (Salvia hispanica L.) oil extraction: study of processing parameters.LWT-Food Sci Technol. 2012;47:78–82. [DOI]
Menga V, Amato M, Phillips TD, Angelino D, Morreale F, Fares C. Gluten-free pasta incorporating chia (Salvia hispanica L.in vitro. 221:1954–61. [DOI] [PubMed]
Dias TR, Alves MG, Casal S, Oliveira PF, Silva BM. Promising potential of dietary (poly)phenolic compounds in the prevention and treatment of diabetes mellitus.Curr Med Chem. 2017;24:334–54. [DOI] [PubMed]
Kwee JK. Yin and yang of polyphenols in cancer prevention: a short review.Anticancer Agents Med Chem. 2016;16:832–40. [DOI] [PubMed]
Aranibar C, Pigni NB, Martinez M, Aguirre A, Ribotta P, Wunderlin D, et al. Utilization of a partially-deoiled chia flour to improve the nutritional and antioxidant properties of wheat pasta.LWT. 2018;89:381–7. [DOI]
Zekrumah M, Begua P, Razak A, Wahab J, Moffo N, Ivane A, et al. Role of dietary polyphenols in non-communicable chronic disease prevention, and interactions in food systems: an overview.Nutrition. 2023;112:112034. [DOI] [PubMed]
Gul K, Singh AK, Jabeen R. Nutraceuticals and functional foods: the foods for the future world.Crit Rev Food Sci Nutr. 2016;56:2617–27. [DOI] [PubMed]
Bucić-Kojić A, Planinić M, Tomas S, Jokić S, Mujić I, Bilić M, et al. Effect of extraction conditions on the extractability of phenolic compounds from lyophilised fig fruits (Ficus Carica L.).Pol J Food Nutr Sci. 2011;61:195–9. [DOI]
Radrigán R, Aqueveque P, Ocampo M. Extraction and use of functional plant ingredients for the development of functional foods. In: Grumezescu AM, Holban AM, editors. Ingredients extraction by physicochemical methods in food. Netherland: Elsevier; 2017. pp.275–306. [DOI]
Belwal T, Chemat F, Venskutonis PR, Cravotto G, Jaiswal DK, Bhatt ID, et al. Recent advances in scaling-up of non-conventional extraction techniques: learning from successes and failures.Trends Analyt Chem. 2020;127:115895. [DOI]
Casazza AA, Aliakbarian B, Mantegna S, Cravotto G, Perego P. Extraction of phenolics from Vitis vinifera wastes using non-conventional techniques.J Food Eng. 2010;100:50–5. [DOI]
Da Porto C, Porretto E, Decorti D. Comparison of ultrasound-assisted extraction with conventional extraction methods of oil and polyphenols from grape (Vitis vinifera L.) seeds.Ultrason Sonochem. 2013;20:1076–80. [DOI] [PubMed]
Khan MK, Abert-Vian M, Fabiano-Tixier AS, Dangles O, Chemat F. Ultrasound-assisted extraction of polyphenols (flavanone glycosides) from orange (Citrus sinesis L.) peel.Food Chem. 2010;119:851–8. [DOI]
Wang L, Weller CL. Recent advances in extraction of nutraceuticals from plants.Trends Food Sci Technol. 2006;17:300–12. [DOI]
Dahmoune F, Spigno G, Moussi K, Remini H, Cherbal A, Madani K. Pistacia lentiscus leaves as a source of phenolic compounds: microwave-assisted extraction optimized and compared with ultrasound-assisted and conventional solvent extraction.Ind Crops Prod. 2014;61:31–40. [DOI]
Pigni NB, Aranibar C, Mas AL, Aguirre A, Borneo R, Wunderlin D, et al. Chemical profile and bioaccessibility of polyphenols from wheat pasta supplemented with partially-deoiled chia flour.LWT. 2020;124:109134. [DOI]
Gámiz-Gracia L, Cuadros-Rodrı́guez L, Almansa-López E, Soto-Chinchilla JJ, Garcı́a-Campaña AM. Use of highly efficient Draper-Lin small composite designs in the formal optimisation of both operational and chemical crucial variables affecting a FIA-chemiluminescence detection system.Talanta. 2003;60:523–34. [DOI] [PubMed]
STATGRAPHICS Centurion XVIII [Internet].Madrid: Statgraphics.Net; c2023 Available from: https://statgraphics.net/
Singleton VL, Orthofer R, Lamuela-Raventós RM. Analysis of total phenols and other oxidation substrates and antioxidants by means of folin-ciocalteu reagents.Methods Enzymol. 1999;299:152–78. [DOI]
Fares C, Platani C, Baiano A, Menga V. Effect of processing and cooking on phenolic acid profile and antioxidant capacity of durum wheat pasta enriched with debranning fractions of wheat.Food Chem. 2010;119:1023–9. [DOI]
Benzie IFF, Strain JJ. The ferric reducing ability of plasma (FRAP) as a measure of “antioxidant power”: the FRAP assay.Anal Biochem. 1996;239:70–6. [DOI] [PubMed]
The R Project for Statistical Computing [Internet].Vienna: The R Foundation; c2023 [cited 2023 Jan 15]. Available from: https://www.R-project.org/
Hasbay I, Galanakis CM. Recovery technologies and encapsulation techniques. In: Galanakis CM, editor. Polyphenols: properties, recovery, and applications. Vienna: Woodhead Publishing; 2018. pp. 233–64. [DOI]
Bartnick DD, Mohler CM, Houlihan M, inventor; Sensient Flavors Inc., assignee. Methods for the production of food grade extracts.European Patent Office WO2006047404. 2005Oct25.
Al-Dhabi NA, Ponmurugan K, Jeganathan PM. Development and validation of ultrasound-assisted solid-liquid extraction of phenolic compounds from waste spent coffee grounds.Ultrason Sonochem. 2017;34:206–13. [DOI] [PubMed]
Tian Y, Liimatainen J, Alanne AL, Lindstedt A, Liu P, Sinkkonen J, et al. Phenolic compounds extracted by acidic aqueous ethanol from berries and leaves of different berry plants.Food Chem. 2017;220:266–81. [DOI] [PubMed]
Yahia EM, Gutiérrez-Orozco F, Moreno-Pérez MA. Identification of phenolic compounds by liquid chromatography-mass spectrometry in seventeen species of wild mushrooms in Central Mexico and determination of their antioxidant activity and bioactive compounds.Food Chem. 2017;226:14–22. [DOI] [PubMed]
Roselló-Soto E, Barba FJ, Parniakov O, Galanakis CM, Lebovka N, Grimi N, et al. High voltage electrical discharges, pulsed electric field, and ultrasound assisted extraction of protein and phenolic compounds from olive kernel.Food Bioproc Tech. 2015;8:885–94. [DOI]
Machado APDF, Duarte Pereira AL, Fernández Barbero G, Martínez J. Recovery of anthocyanins from residues of Rubus fruticosus, Vaccinium myrtillus and Eugenia brasiliensis by ultrasound assisted extraction, pressurized liquid extraction and their combination.Food Chem. 2017;231:1–10. [DOI] [PubMed]
Corona-Jiménez E, Martínez-Navarrete N, Ruiz-Espinosa H, Carranza-Concha J, Ultrasound-assisted extraction of phenolics compounds from chia (Salvia hispanica L. ) seeds and their antioxidant activity.Agrociencia. 2016;50:403–12.
Reyes-Caudillo E, Tecante A, Valdivia-López MA. Dietary fibre content and antioxidant activity of phenolic compounds present in Mexican chia (Salvia hispanica L.) seeds.Food Chem. 2008;107:656–63. [DOI]
Albu S, Joyce E, Paniwnyk L, Lorimer JP, Mason TJ. Potential for the use of ultrasound in the extraction of antioxidants from Rosmarinus officinalis for the food and pharmaceutical industry.Ultrason Sonochem. 2004;11:261–5. [DOI] [PubMed]
Alothman M, Bhat R, Karim AA. Antioxidant capacity and phenolic content of selected tropical fruits from Malaysia, extracted with different solvents.Food Chem. 2009;115:785–8. [DOI]
Routray W, Orsat V. MAE of phenolic compounds from blueberry leaves and comparison with other extraction methods.Ind Crops Prod. 2014;58:36–45. [DOI]
Ramil Criado M, Pombo da Torre S, Rodríguez Pereiro I, Cela Torrijos R. Optimization of a microwave-assisted derivatization–extraction procedure for the determination of chlorophenols in ash samples.J Chromatogr A. 2002;1024:155–63. [DOI] [PubMed]
Zhou HY, Liu CZ. Microwave-assisted extraction of solanesol from tobacco leaves.J Chromatogr A. 2006;1129:135–9. [DOI] [PubMed]
Akbari S, Abdurahman NH, Yunus MR. Optimization of saponins, phenolics, and antioxidants extracted from fenugreek seeds using microwave-assisted extraction and response surface methodology as an optimizing tool.C R Chimie. 2019;22:714–27. [DOI]
Kaderides K, Papaoikonomou L, Serafim M, Goula AM. Microwave-assisted extraction of phenolics from pomegranate peels: optimization, kinetics, and comparison with ultrasounds extraction.Chem Eng Process Process Intensif. 2019;137:1–11. [DOI]
Proestos C, Komaitis M. Application of microwave-assisted extraction to the fast extraction of plant phenolic compounds.LWT-Food Sci Technol. 2018;41:652–9. [DOI]
Guindani C, Podestá R, Block JM, Rossi MJ, Mezzomo N, Ferreira SRS. Valorization of chia (Salvia hispanica) seed cake by means of supercritical fluid extraction.J Supercrit Fluids. 2016;112:67–75. [DOI]
