Table Info

Table 4.

Compounds identified by HPLC-MS in U. tuberosus and A. xanthorrhiza

RT (min)	m/z	Compound	Family	*U. tuberosus*		*A. xanthorrhiza*
RT (min)	m/z	Compound	Family	Flour	Husk	Flour	Husk
4.39	341.1	Caffeic acid 4-O-glucoside	Hydroxycinnamic acids	+	+	+	+
5.22	353.1	1-Caffeoylquinic acid	Hydroxycinnamic acids	-	-	+	+
6.09	110.9	Catechol	Other polyphenols	-	+	-	-
6.23	191.0	Scopoletin	Hydroxycoumarins	-	+	-	-
18.34	380.1	Tectorigenin 4’-sulfate	Flavonols	-	+	-	-
19.13	382.1	Quercetin 3’-sulfate	Flavonols	-	-	+	-
19.56	365.1	Secoisolariciresinol	Lignans	-	-	+	-
20.74	359.0	Lariciresinol	Lignans	-	+	-	-
21.01	371.2	Sesamolinol	Lignans	-	-	+	-
31.34	355.1	Ferulic acid 4-O-glucoside	Methoxycinnamic acids	-	+	-	-
32.68	755.1	Quercetin 3-O-rhamnosyl-rhamnosyl-glucoside	Flavonols	-	+	-	-
34.90	739.2	Kaempferol 3-O-xylosyl-rutinoside	Flavonols	+	+	-	-
35.33	371.2	Sinensetin	Methoxyflavones	+	-	-	-
35.78	385.2	5-5’-Dehydrodiferulic acid	Methoxycinnamic acid dimers	-	-	+	-
36.05	609.1	Quercetin 3-O-rutinoside	Flavonols	-	+	-	-
38.10	453.2	d-Viniferin	Stilbene dimers	-	-	-	+
40.95	341.1	Tetramethylscutellarein	Methoxyflavones	-	-	+	-
41.24	329.3	3,7-Dimethylquercetin	Methoxyflavonols	+	+	+	+
46.57	325.3	p-Coumaroyl glucose	Hydroxycinnamic acids	+	+	+	+
48.41	325.1	Feruloyl tartaric acid	Methoxycinnamic acids	+	-	-	-
49.86	325.2	p-Coumaric acid 4-O-glucoside	Hydroxycinnamic acids	+	-	-	-
51.81	327.2	p-Coumaroyl tyrosine	Hydroxycinnamic acids	-	+	-	-
53.96	311.3	Caffeoyl tartaric acid	Hydroxycinnamic acids	-	-	+	-

Ratio of solid/liquid (1:14, absolute ethanol 50% and water 50%). RT: retention time; HPLC-MS: liquid chromatography-mass spectrometry. +: presence; -: absence

Declarations

Acknowledgments

SSP gratefully acknowledges the financial support of the Consejo Nacional de Ciencia y Tecnología de México (CONACyT) for graduate studies.

Author contributions

SSP: Conceptualization, Investigation, Supervision, Writing—original draft. RRH: Conceptualization, Data curation, Funding acquisition, Project administration, Resources, Supervision, Writing—original draft, Writing—review & editing. MdRSS: Methodology, Supervision, Writing—review & editing. LGCM: Formal analysis, Methodology, Validation. ACFG: Investigation, Software, Validation, Writing—review & editing. JFSD: Conceptualization, Funding acquisition, Project administration, Resources. JAAV: Investigation, Software. CMLB: Formal analysis, Methodology, Software, Validation.

Conflicts of interest

The authors declare that they have no financial interests or personal relationships that might appear to influence the work presented in this article.

Ethical approval

Not applicable.

Consent to participate

Not applicable.

Consent to publication

Not applicable.

Availability of data and materials

The raw data supporting the conclusions of this manuscript will be made available by the authors, without undue reservation, to any qualified researcher.

Funding

This study was funded by the Universidad Autónoma de Coahuila-Mexico [15495] and the Universidad del Cauca-Colombia [7552689]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Copyright

References

Sáenz-Torres S, López-Molinello A, Prieto-Contreras L, Rodríguez T. El Cubio Como Una Alternativa Productiva Sostenible En Condiciones de Agricultura Urbana de Bogotá. Equidad y Desarrollo. 2019;1:121–42. Spanish. [DOI]

Euder HH. Influencia Del Nitrógeno y Fósforo En El Comportamiento Agronómico Del Frijol Caupí (Vigna Unguiculata L. Walp) En Cieneguillo Centro-Sullana-2019 [dissertation]. São Paulo: Universidad San Pedro; 2021. Spanish.

Clavijo Ponce NL. Cultura y Conservación in Situ de Tubérculos Andinos Marginados En Agroecosistemas de Boyacá: Un Análisis de Su Persistencia Desde La Época Prehispánica Hasta El Año 2016. Cuadernos de Desarrollo Rural. 14:1–19. [DOI]

Sanchez-Portillo S, del Rosario Salazar-Sánchez M, Solanilla-Duque JF, Rodríguez-Herrera R. Andean Tubers, Morphological Diversity, and Agronomic Management: A Review. Plant Science Today. 2023;10:98–105. [DOI]

Bonete M, Urquizo C, Guevara R, Yanez P. Estudio De Cuatro Tubérculos Y Raíces Tuberosas No Tradicionales De La Sierra Centro De Ecuador Y Su Potencial de Uso En Platos de Autor. Estudio de cuatro tubérculos y raíces tuberosas no tradicionales. 2016;12:37–67. Spanish.

Velásquez-Barreto FF, Bello-Pérez LA, Nuñez-Santiago C, Yee-Madeira H, Velezmoro Sánchez CE. Relationships among Molecular, Physicochemical and Digestibility Characteristics of Andean Tuber Starches. Int J Biol Macromol. 2021;182:472–81. [DOI] [PubMed]

Parra-Quijano M, Panda S, Rodríguez N, Torres E. Diversity of Ullucus Tuberosus (Basellaceae) in the Colombian Andes and Notes on Ulluco Domestication Based on Morphological and Molecular Data. Genet Resour Crop Evol. 2012;59:49–66. [DOI]

Barrera VH, Tapia CG, Monteros AR, editors. Caracterización de las raíces y los tubérculos andinos en la ecoregión andina del Ecuador. In: Raíces y Tubérculos Andinos: Alternativas Para La Conservación y Uso Sostenible En El Ecuador. Lima: Centro Internacional de la Papa; 2004. pp. 3–30. Spanish.

Campos D, Chirinos R, Gálvez Ranilla L, Pedreschi R. Bioactive Potential of Andean Fruits, Seeds, and Tubers. Adv Food Nutr Res. 2018;84:287–343. [DOI] [PubMed]

10.

Galindez A, Daza LD, Homez-Jara A, Eim VS, Váquiro HA. Characterization of Ulluco Starch and Its Potential for Use in Edible Films Prepared at Low Drying Temperature. Carbohydr Polym. 2019;215:143–50. [DOI]

11.

Heil N, Bravo K, Montoya A, Robledo S, Osorio E. Wound Healing Activity of Ullucus Tuberosus, an Andean Tuber Crop. Asian Pac J Trop Biomed. 2017;7:538–43. [DOI]

12.

Pacheco MT, Hernández-Hernández O, Moreno FJ, Villamiel M. Andean Tubers Grown in Ecuador: New Sources of Functional Ingredients. Food Biosci. 2020;35:100601. [DOI]

13.

Repo-Carrasco R. Cultivos Andinos. Importancia nutricional y posibilidades de procesamiento. Cusco: Centro Bartolomé de las Casas; 1988.

14.

Pacheco MT, Moreno FJ, Moreno R, Villamiel M, Hernandez-Hernandez O. Morphological, Technological and Nutritional Properties of Flours and Starches from Mashua (Tropaeolum Tuberosum) and Melloco (Ullucus Tuberosus) Cultivated in Ecuador. Food Chem. 2019;301:125268. [DOI] [PubMed]

15.

Campos D, Noratto G, Chirinos R, Arbizu C, Roca W, Cisneros-Zevallos L. Antioxidant Capacity and Secondary Metabolites in Four Species of Andean Tuber Crops: Native Potato (Solanum Sp.), Mashua (Tropaeolum Tuberosum Ruiz & Pavón), Oca (Oxalis Tuberosa Molina) and Ulluco (Ullucus Tuberosus Caldas). J Sci Food Agric. 2006;86:1481–8.

16.

Goicochea Chuquilin RC, Carolim M, Teodoro J. Propiedades Funcionales de Productos Tradicionales Congelados y Secados al Sol de Oca (Oxalis Tuberosa Molina ) y Olluco (Ullucus Tuberosus Caldas ): Una Revisión. Puriq. 2020;2:247–63. Spanish. [DOI]

17.

González Cabrera MV, Moreno Andrade GI, López Sampedro SE. Caracterización Nutricional y Funcional de La Harina de Mashua. ConcienciaDigital. 2020;3:199–214. Spanish. [DOI]

18.

Mosquera N, Cejudo-Bastante MJ, Heredia FJ, Hurtado N. Identification of New Betalains in Separated Betacyanin and Betaxanthin Fractions from Ulluco (Ullucus Tuberosus Caldas) by HPLC-DAD-ESI-MS. Plant Foods Hum Nutr. 2020;75:434–40. [DOI] [PubMed]

19.

Tribst AAL, de Castro Leite Júnior BR, De Oliveira MM, Cristianini, M. High Pressure Processing of Cocoyam, Peruvian Carrot and Sweet Potato: Effect on Oxidative Enzymes and Impact in the Tuber Color. Innovative Food Sci Emerging Technol. 2016;34:302–9. [DOI]

20.

Apak R, Özyürek M, Güçlü K, Çapanoğlu E. Antioxidant Activity/Capacity Measurement. 1. Classification, Physicochemical Principles, Mechanisms, and Electron Transfer (ET)-Based Assays. J Agric Food Chem. 2016;64:997–1027. [DOI] [PubMed]

21.

Soriano Sancho RA, Souza JDRP, de Lima FA, Pastore GM. Evaluation of Oligosaccharide Profiles in Selected Cooked Tubers and Roots Subjected to in Vitro Digestion. LWT-Food Science and Technology. 2017;76:270–7. [DOI]

22.

de Camargo AC, Vidal CMM, Canniatti-Brazaca SG, Shahidi F. Fortification of cookies with peanut skins: Effects on the composition, polyphenols, antioxidant properties, and sensory quality. J Agric Food Chem. 2014;62:11228–35. [DOI] [PubMed]

23.

Michel-Michel MR, Aguilar-Zárate P, Lopez-Badillo CM, Chávez-González ML, Flores-Gallegos AC, Espinoza-Velázquez J, et al. Mineral and Fatty Acid Contents of Maize Kernels with Different Levels of Polyembryony. Cereal Chem. 2020;97:723–32. [DOI]

24.

Salas YA, Colque MC, Lazo AB. Obtención y caracterización fisicoquímica y funcional de las fibras dietéticas del níspero común (Mespilus germanica). Revista de la Sociedad Química del Perú. 2008;74:269–81. Spanish.

25.

Requena MC, González CNA, Barragán LAP, Correia T, Esquivel JCC, Herrera RR. Functional and Physico-Chemical Properties of Six Desert-Sources of Dietary Fiber. Food Biosci. 2016;16:26–31. [DOI]

26.

Garcia-Ortiz JD, Flores-Gallegos AC, Ascacio-Valdés JA, López-Badillo CM, Nery-Flores SD, Esparza-González SC, et al. Microwave-Ultrasound Assisted Extraction of Red Corn Pigments and Their Effect on Chemical Composition and Tecno-Functional Properties. Food Biosci. 2022;50:102115. [DOI]

27.

Ascacio-Valdés JA, Aguilera-Carbó AF, Buenrostro JJ, Prado-Barragán A, Rodríguez-Herrera R, Aguilar CN. The Complete Biodegradation Pathway of Ellagitannins by Aspergillus Niger in Solid-State Fermentation. J Basic Microbiol. 2016;56:329–36. [DOI] [PubMed]

28.

Leidi EO, Altamirano AM, Mercado G, Rodriguez JP, Ramos A, Alandia G, et al. Andean Roots and Tubers Crops as Sources of Functional Foods. J Funct Foods. 2018;51:86–93. [DOI]

29.

Velásquez-Barreto FF, Bello-Pérez LA, Yee-Madeira H, Velezmoro Sánchez CE. Esterification and Characterization of Starch From Andean Tubers. Starch/Staerke. 2019;71:1800101. [DOI]

30.

Chaali N, Ouazaa S, Jaramillo-Barrios CI, Araujo Carrillo GA, Ávila Pedraza EÁ. Edaphoclimatic Characterization and Crop Water Requirement of Arracacha (Arracacia Xanthorrhiza Bancroft) Roots in Upland Production Areas. Sci Hortic. 2020;272:109533. [DOI]

31.

Luo X, Cheng B, Zhang W, Shu Z, Wang P, Zeng X. Structural and Functional Characteristics of Japonica Rice Starches with Different Amylose Contents. CYTA-Journal of Food. 2021;19:532–40. [DOI]

32.

Ojeda L, Claramonte M, Rey J, Trestini C, Useche M, Zambrano N, et al. Effect of the Freezing and Thawing Processes on Starches in a Corn-Based Food. Revista Chilena de Nutricion. 2018;45:310–5. Spanish. [DOI]

33.

Scortegagna ML, de Oliveira VR, Pasini I, Silva M, de Oliveira Rios A, Doneda D. Low Phenylalanine Breads as an Alternative for Patients with Phenylketonuria. British Food Journal. 2020;122:26–35. [DOI]

34.

del C. Coutiño Laguna B, Flores Gallegos AC, Ascacio Valdés JA, Iliná A, Galindo AS, Castañeda Facio AO, et al. Coutiño Laguna B, Flores Gallegos AC, Ascacio Valdés JA, Iliná A, Galindo AS, Castañeda Facio AO, et al. Physicochemical and Functional Properties of the Undervalued Fruits of Cactus Cylindropuntia Imbricate (“Xoconostle”) and Antioxidant Potential. Biocatal Agric Biotechnol. 2022;39:102245. [DOI]

35.

Kant S, Kafkafi U. Absorcion de potasio por los cultivos endistintos estadios fisiologicos. Potasio en plantas animales [Internet]. 2006 [cited 2022 Nov 23]. Available from: https://www.ipipotash.org/uploads/udocs/Sesion%20V.pdf

36.

Perasso Padilla CS. Investigación Del Procedimiento Óptimo Para La Disminución de La Concentración de Potasio En Patata, Zanahoria y Yuca Sometidas a Cocción [dissertation]. Quito: Universdad Central Del Ecuador; 2019. Spanish.

37.

Ana Cruz Morillo C, Yacenia Morillo C, Leguizamo MF. Caracterización Morfológica y Molecular de Oxalis Tuberosa Mol. En El Departamento de Boyacá. Rev Colomb Biotecnol. 2019;21:18–28. [DOI]

38.

Lovera M, Pérez E, Laurentin A. Digestibility of Starches Isolated from Stem and Root Tubers of Arracacha, Cassava, Cush–Cush Yam, Potato and Taro. Carbohydr Polym. 2017;176:50–5. [DOI] [PubMed]

39.

Andrade-Mahecha MM, Tapia-Blácido DR, Menegalli FC. Physical-Chemical, Thermal, and Functional Properties of Achira (Canna Indica L.) Flour and Starch from Different Geographical Origin. Starch/Staerke. 2012;64:348–58. [DOI]

40.

Salazar Rodríguez Y, Alfonso Martinez J, Gallardo Cruz A. Biostimulants. An Alternative for Cuban Agroecological Development. Ecovida. 2021;11:225–49. Spanish.

41.

Fabersani E, Grande MV, Coll Aráoz MV, Zannier ML, Sánchez SS, Grau A, et al. Metabolic Effects of Goat Milk Yogurt Supplemented with Yacon Flour in Rats on High-Fat Diet. J Funct Foods. 2018;49:447–57. [DOI]

42.

Padilha VM, Andrade SAC, Valencia MS, Stamford TLM, Salgado SM. Optimization of Synbiotic Yogurts with Yacon Pulp (Smallanthus Sonchifolius) and Assessment of the Viability of Lactic Acid Bacteria. Food Science and Technology. 2017;37:166–75. [DOI]

43.

Espín S, Villacrés E, Brito B. Caracterización Físico-Química, Nutricional y Funcional de Raíces y Tubérculos Andinos. In: Barrera VH, Tapia C, Monteros y A, editors. Raíces y Tubérculos Andinos: Alternativas para la conservación y uso sostenible en el Ecuador. Quito: INIAP/CIP/COSUDE; 2004. pp. 91–116. Spanish.

44.

Carlos Zehnder B. Sodio, Potasio e Hipertensión Arterial. Revista Médica Clínica Las Condes. 2010;21:508–15. [DOI]

45.

Sawicka B, Hulail Noaema A, Seead Hameed T, Skiba D. Genotype and environmental variability of chemical elements in potato tubers. Acta Sci Pol Agricultura. 2016;15:79–91.

46.

Soares JC, Santos CS, Carvalho SMP, Pintado MM, Vasconcelos MW. Preserving the Nutritional Quality of Crop Plants under a Changing Climate: Importance and Strategies. Plant Soil. 2019;443:1–26. [DOI]

47.

Renee Vidal A, Zaucedo-Zuñiga AL, de Lorena Ramos-García M. Nutrimental properties of the sweet potato (Ipomoea batatas L.) and its benefits in human health. Revista Iberoamericana de Tecnología Postcosecha. 2018;19:2. Spanish.

48.

Valcárcel-Yamani B, Rondán-Sanabria GG, Finardi-Filho F. The Physical, Chemical and Functional Characterization of Starches from Andean Tubers: Oca (Oxalis Tuberosa Molina), Olluco (Ullucus Tuberosus Caldas) and Mashua (Tropaeolum Tuberosum Ruiz & Pavón). Brazilian Journal of Pharmaceutical Sciences. 2013;49:453–64. [DOI]

49.

Torres-León C, Rojas R, Serna-Cock L, Belmares-Cerda R, Aguilar CN. Extraction of Antioxidants from Mango Seed Kernel: Optimization Assisted by Microwave. Food and Bioproducts Processing. 2017;105:188–96. [DOI]

50.

Chaves WF. Exposição materna à dieta hipercalórica e hiperlipídica e administração neonatal de Kaempferol: aspectos somáticos, bioquímicos e do comportamento alimentar [dissertation]. Recife: Universidad federal de pernambuco; 2020. Spanish.

51.

Imran M, Salehi B, Sharifi-Rad J, Gondal TA, Saeed F, Imran A, et al. Kaempferol: A Key Emphasis to Its Anticancer Potential. Molecules. 2019;24:2277. [DOI] [PubMed] [PMC]

52.

Chumillas S, Palomäki T, Zhang M, Laurila T, Climent V, Feliu JM. Analysis of Catechol, 4-Methylcatechol and Dopamine Electrochemical Reactions on Different Substrate Materials and PH Conditions. Electrochim Acta. 2018;292:309–21. [DOI]

53.

Conejo-Cuevas G, Ruiz-Rubio L, Sáez-Martínez V, Pérez-González R, Gartziandia O, Huguet-Casquero A, et al. Spontaneous Gelation of Adhesive Catechol Modified Hyaluronic Acid and Chitosan. Polymers. 2022;14:1209. [DOI] [PubMed] [PMC]

54.

Lim HS, Kim YJ, Kim BY, Park G, Jeong SJ. The Anti-Neuroinflammatory Activity of Tectorigenin Pretreatment via Downregulated NF-ΚB and ERK/JNK Pathways in BV-2 Microglial and Microglia Inactivation in Mice with Lipopolysaccharide. Front Pharmacol. 2018;9:462. [DOI] [PubMed] [PMC]

55.

Sakthivel KM, Vishnupriya S, Chandramani L, Dharshini P, Rasmi RR, Ramesh B. Modulation of Multiple Cellular Signalling Pathways as Targets for Anti-Inflammatory and Anti-Tumorigenesis Action of Scopoletin. J Pharm Pharmacol. 2022;74:147–61. [DOI] [PubMed]

56.

Abramovič H. Antioxidant Properties of Hydroxycinnamic Acid Derivatives: A Focus on Biochemistry, Physicochemical Parameters, Reactive Species, and Biomolecular Interactions. In: Preedy VR, editor. Coffee in Health and Disease Prevention. San Diego: Academic Press; 2015. pp. 843–52. [DOI]

57.

Vitelli-Storelli F, Zamora-Ros R, Molina AJ, Fernández-Villa T, Castelló A, Barrio JP, et al. Association between Polyphenol Intake and Breast Cancer Risk by Menopausal and Hormone Receptor Status. Nutrients. 2020;12:994. [DOI] [PubMed] [PMC]

58.

Zamora-Ros R, Andres-Lacueva C, Lamuela-Raventós RM, Berenguer T, Jakszyn P, Martíez C, et al. Concentrations of resveratrol and derivatives in foods and estimation of dietary intake in a Spanish population: European Prospective Investigation into Cancer and Nutrition (EPIC)-Spain cohort. Br J Nutr. 2008;100:188–96. [DOI] [PubMed]

59.

Robles Solano E. Caracterización de Compuestos Fenólicos En Extractos de Origen Vegetal [dissertation]. Jaén: Universidad de Jaén; 2021. Spanish.

60.

Pacheco MT, Escribano-Bailón MT, Moreno FJ, Villamiel M, Dueñas M. Determination by HPLC-DAD-ESI/MSn of Phenolic Compounds in Andean Tubers Grown in Ecuador. J Food Compos Anal. 2019;84:103258. [DOI]

61.

Fuentalba Carrasco CV. Determinación de la bióaccesibilidad de lignanos de linaza mediante una simulación in vitro del proceso digestivo [dissertation]. Santiago: Universidad de Santiago de Chile; 2015. Spanish.

62.

Rojas Muñoz FS. Revisión bibliográfica de compuestos fenólicos, su efecto en la salud, métodos de encapsulación y digestión simulada in vitro. [dissertation]. Santiago: Universidad de Chile; 2021. Spanish.

63.

Baeza G, Bachmair EM, Wood S, Mateos R, Bravo L, De Roos B. The Colonic Metabolites Dihydrocaffeic Acid and Dihydroferulic Acid Are More Effective Inhibitors of in Vitro Platelet Activation than Their Phenolic Precursors. Food Funct. 2017;8:1333–42. [DOI] [PubMed]

64.

Pandith H, Zhang X, Thongpraditchote S, Wongkrajang Y, Gritsanapan W, Baek SJ. Effect of Siam Weed Extract and Its Bioactive Component Scutellarein Tetramethyl Ether on Anti-Inflammatory Activity through NF-ΚB Pathway. J Ethnopharmacol. 2013;147:434–41. [DOI] [PubMed]

65.

Duque L, Bravo K, Osorio E. A Holistic Anti-Aging Approach Applied in Selected Cultivated Medicinal Plants: A View of Photoprotection of the Skin by Different Mechanisms. Ind Crops Prod. 2017;97:431–9. [DOI]

66.

Leonel M, do Carmo EL, Franco CML, Fernandes AM, Garcia EL, dos Santos TPR. Peruvian Carrot (Arracacia Xanthorrhiza Bancroft) as Raw Material for Producing Special Native Starches. Aust J Crop Sci. 2016;10:1151–7. [DOI]

67.

Chacón Orduz G, Muñoz Rincón A, Quiñónez Mosquera GA. Descripción Del Mercado de Los Snacks Saludables En Villavicencio, Meta. Libre Empresa. 2017;14:33–45. [DOI]

68.

Coyago E. Estudio Sobre El Contenido En Carotenoides y Compuestos Fenólicos de Tomates y Flores En El Contexto de La Alimentación Funcional [dissertation]. San Fernando: Universidad de Sevilla; 2017. Spanish.

69.

Márquez Fernández PM, Fer M, Nández DM. Functional Foods: Current Issues and Trends. Vitae. 2019;26:6–7. [DOI]