Table Info

Table 4.

Pharmaceutical substances (ng L^–1) detected in real fish farm seawater samples during annual sampling

Compounds	July 2020	August 2020	September 2020	October 2020	November 2020	December 2020	January 2021	February 2021	March 2021	April 2021	May 2021	June 2021
Erythromycin-H₂O	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD
Oxolinc acid	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD
Oxytetracycline	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	43,817	< LOD	< LOD	< LOD	< LOD
N-Acetyl sulfamethoxazole (M)	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD
Sulfadiazine	< LOD	< LOD	145.4	< LOD	< LOD	< LOD	< LOD	1,092	< LOD	411.3	339.3	< LOD
Sulfamethazine	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD
Sulfamethizole	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD
Sulfamethoxazole	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD
Sulfamethoxypyridazine	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD
Sulfapyridine	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD
Sulfaquinoxaline	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD
Sulfathiazole	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD
Trimethoprim	< LOD	< LOD	< LOD	< LOQ	< LOD	< LOD	< LOD	32.6	< LOD	< LOQ	34.2	< LOD
Caffeine	< LOQ	< LOD	< LOQ	< LOQ	< LOQ	< LOQ	< LOD	< LOD	< LOD	< LOD	< LOQ	< LOQ
Paracetamol	< LOD	< LOD	< LOD	< LOD	< LOD	< LOQ	< LOQ	< LOD	< LOD	< LOD	< LOD	< LOD
Phenazone	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD
Carbamazepine	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD
Carbamazepine-10.11-epoxide (Μ)	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD
Citalopram	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD
Fluoxetine	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD
N-Desmethyl sertraline (M)	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD
Norfluoxetine (M)	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD
O-Desmethyl venlafaxine (M)	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD
Sertraline	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD
Venlafaxine	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD	< LOD

LOD: limits of detection; LOQ: limits of quantification. Positive findings are given in bold

Supplementary materials

The supplementary material for this article is available at: https://www.explorationpub.com/uploads/Article/file/101061_sup_1.pdf.

Declarations

Acknowledgments

This research was co-financed by Greece and the European Union (European Social Fund-ESF) through the Operational Programme «Human Resources Development. Education and Lifelong Learning» in the context of the project “Strengthening Human Resources Research Potential via Doctorate Research” (MIS-5000432). Implemented by the State Scholarships Foundation (ΙΚΥ). The authors would like to thank the Unit of Environmental. Organic and Biochemical High-Resolution Analysis-Orbitrap-LC-MS of the University of Ioannina for providing access to the facilities.

Author contributions

AK: Validation, Formal analysis, Investigation, Writing—original draft, Writing—review & editing, Visualization. CK: Methodology, Formal analysis, Visualization, Writing—original draft, Writing—review & editing. TA: Conceptualization, Methodology, Visualization, Supervision, Resources, Funding acquisition.

Conflict of interest

The authors declare no competing interests.

Ethical approval

Not applicable.

Consent to participate

Not applicable.

Consent to publication

Not applicable.

Availability of data and materials

All relevant data is contained within the manuscript.

Funding

This research is co-financed by Greece and the European Union (European Social Fund-ESF) through the Operational Programme “Human Resources Development. Education and Lifelong Learning” in the context of the project “Strengthening Human Resources Research Potential via Doctorate Research” [MIS-5000432]. Implemented by the State Scholarships Foundation (ΙΚΥ). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Copyright

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