In vivo human studies using lymphocyte γ-H2AX foci as the assay type
Author, year | N (with and without ICM) | Equipment | Dose | ICM type | Iodine dose administered (g) | Results | Reference |
---|---|---|---|---|---|---|---|
Grudzenski et al., 2009 | 19/18 | Philips MX 8000 CT | 287/480 mGy*cm2 | Iopromide | 34.9 | +30% | [16] |
Pathe et al., 2011 | 15/15 | Siemens Somaton 10 or 64 | 336–392 mGy*cm2 | Iopromide | 37–44.4 | +58% | [17] |
Gould et al., 2016 | 57/12 | Philips Allura Xper (fluoroscopy) | 116 mGy*cm2 | Iomeprol | 19 | - | [20] |
Piechowiak et al., 2015 | 179/66 | Siemens Sensation 64 (CT) | 301–342 mGy*cm2 | Iopromide | 18.6 | +267% | [27] |
Wang et al., 2017 | 48/22 | Siemens Sensation 64 (CT) | 294 mGy*cm2 | Iopromide | 33 | +38% | [28] |
Van Cauteren et al., 2021 | 45/5 | Coronary CT in humans | 11.3 mGy ± 5.3 mGy | Iopromide, iobitridol, iomeprol | 16.5–34.0 | - | [29] |
-: blank cell
CI: Conceptualization, Writing—original draft. MX, VP, and EC: Writing—review & editing.
The authors declare that there are no conflicts of interest.
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© The Author(s) 2024.