Table Info

Table 4.

Medications used, ventilator settings, and ECMO settings throughout the course of treatment

Clinical characteristics	Extubated on ECMO (N = 14)	Remain Intubated on ECMO (N = 11)	p-value
Sedation medications dosages
Propofol (mcg/kg/min)	55 ± 14	59 ± 15	0.42
Versed (mg/kg)	0.079 ± 0.033	0.11 ± 0.077	0.56
Fentanyl (mcg)	184 ± 57	175 ± 77	0.92
Paralyzed			0.99
No	3 (21%)	2 (18%)
Yes	11 (79%)	9 (82%)
Vasoactive drugs dosages
Norepinephrine (mcg/kg/min)	0.034 ± 0.022	0.12 ± 0.093	0.04
Epinephrine (mcg/kg/min)	0.16 ± 0.05	0.1 ± 0.03	0.99
Days on ventilator	19 ± 14	59 ± 41	0.012
Type ECMO			0.42
VV-bicaval	2 (14%)	2 (18%)
VV-bifemoral	0	1 (9%)
VV-protek duo	12 (86%)	7 (64%)
VA	0	1 (9%)
Total days on ECMO	32 ± 14	51 ± 37	0.31
Tidal Volume day 14 (mL)	233 ± 119	166 ± 140	0.22
Tidal Volume day 28 (mL)	212 ± 73	239 ± 127	0.95
ECMO settings at time extubation for group A
Flow (L/min)	4.8 ± 0.77	4.4 ± 0.95
FiO₂ (%)	88 ± 16	80 ± 34
Sweep (L)	3.8 ± 3.7	6 ± 4.9
Ventilator (oxygen) settings at the time of decannulation for group B (group A extubated)
FiO₂ (%)	44 ± 12	41 ± 3.2
Pressure support (cmH₂O)	N/A	14 ± 3.5
PEEP (cmH₂O)	N/A	7.9 ± 2.2

1 cmH₂O = 0.0980665 kPa. ECMO: extracorporeal membrane oxygenation; VV: veno-venous; VA: veno-arterial; PEEP: positive end expiratory pressure; FiO₂: fraction inspired; N/A: not applicable

Declarations

Author contributions

SK, AP, and CB: Writing—original draft, Writing—review & editing. CD, CN, RW, MF, and OF: Data curation, Investigation. SZ: Formal analysis. All authors read and approved the submitted version.

Conflicts of interest

The authors declare that they have no conflicts of interest.

Ethical approval

The study was approved by the Penn State Health Institutional Review Board and the Study ID number is STUDY00021063.

Consent to participate

No consent was needed from participants of this study as this was an observational, retrospective study and this waiver of consent was accepted during the IRB review.

Consent to publication

Not applicable.

Availability of data and materials

The datasets generated for this study are available upon request to the corresponding author.

Funding

Not applicable.

Copyright

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Open Exploration maintains a neutral stance on jurisdictional claims in published institutional affiliations and maps. All opinions expressed in this article are the personal views of the author(s) and do not represent the stance of the editorial team or the publisher.

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