Echocardiographic differences between the group with cardiotoxicity and the group without cardiotoxicity
Variables
Patients with cardiotoxicity
Patients without cardiotoxicity
P
Diastolic diameter (mm)
43.3 ± 5.7
42.6 ± 5
0.254
Systolic diameter (mm)
27.6 ± 6.3
27.0 ± 5.1
0.383
Septum (mm)
8.2 ± 2.1
8.4 ± 1.4
0.362
Posterior wall (mm)
8 ± 1.4
8.2 ± 1.4
0.275
Left ventricular mass (g/m2)
71.1 ± 15.7
66 ± 16.7
0.127
RWT
0.38 ± 0.11
0.38 ± 0.08
0.418
LVEF (%)
58.6 ± 10.6
63.7 ± 6
0.005
GLS (%)
13.9 ± 1.9
19.4 ± 4.2
< 0.001
Postsystolic contractions
74.5%
16.5%
< 0.001
GWI (mmHg%)
1,421.4 ± 396.7
1,925.4 ± 448
< 0.001
GCW (mmHg%)
1,669.6 ± 399
2,115.1 ± 484
< 0.001
GWW (mmHg%)
179.8 ± 106.7
135.3 ± 106
0.015
GWE (%)
88.2 ± 5
104.6 ± 138
0.246
Mechanical dispersion (ms)
76.7 ± 35
47.3 ± 15.9
< 0.001
RWT: relative wall thickness; LVEF: left ventricular ejection fraction; GLS: global longitudinal strain; GWI: global myocardial work index; GCW: Global Constructive Work; GWW: Global Wasted Work; GWE: Global Work Efficiency
We would like to express our gratitude to the entire echocardiography service at the Cabinet Department of the National Medical Center 21st century as they were instrumental in-patient recruitment during this time. We also want to thank Dr. Daniel Calderón Rodríguez from the Nuclear Medicine service at the Cardiology Hospital, National Medical Center 21st century, and Dr. Rubén Fernández Galera from Vall d’Hebron Hospital for their contribution with nuclear medicine and cardiac magnetic resonance images.
The authors declare that they have no conflicts of interest.
Ethical approval
The study was approved by the local health research committee 3604, Cardiology Hospital National Medical Center 21st century, Registration number R-2023-3604-056.
Consent to participate
Informed consent to participate in the study was obtained from all participants.
Consent to publication
Not applicable.
Availability of data and materials
We have the database of this study electronically, if you need this or revision of any data, we will gladly send it to you, contact dnicrck@hotmali.com.
Open Exploration maintains a neutral stance on jurisdictional claims in published institutional affiliations and maps. All opinions expressed in this article are the personal views of the author(s) and do not represent the stance of the editorial team or the publisher.
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