A summary of electrospinning methods used for sythetic biomaterials for heart valve tissue engineering

PolymerCollector typeOrientation of nanofiberCell typeReferences
PGS-PCLConventional collector (aluminum plate)Non-alignedHuman umbilical vein endothelial cells (HUVECs)Sant et al., 2011 [125]
PGS-PCLConventional collector (aluminum plate)Non-alignedValve interstitial cells (VICs)Sant et al., 2013 [126]
PGS-PCLTeflon sheet collectorAlignedVICsMasoumi et al., 2014 [83]
PCLSpoke-in-ring collectorAlignedVICsJana and Lerman, 2016 [127]
PCL-PLLAConventional collector (aluminum plate)Non-alignedPorcine valve interstitial cells (PVICs) and C57/B1 mice cardiac stem cells (CSCs)Hasan et al., 2018 [128]
PCLRing-with-dot collectorAlignedPVICsJana and Lerman, 2019 [129]
PCLConventional collector (metal plate)Non-alignedPVICsJana et al., 2019 [130]
PCL-gelatinCentrifugal jet spinner setup-reservoir surfaceAlignedPVICsRavishankar et al., 2021 [78]
PCLConventional collector (aluminum plate)Non-alignedHuman endothelial colony-forming cells (ECFCs) and human induced-pluripotent stem cells-derived MSCs (iMSCs)Lutter et al., 2022 [131]
PCL/PGS/PSfCentered pillar collectorAlignedHUVECsGürbüz et al., 2024 [88]

PGS: poly(glycerol) sebacate; PCL: polycaprolactone; PLLA: poly L-lactic acid; PSf: polysulfone