Table Info

Table 4.

The number of hypomethylated (< 50%) and hypermethylated (> 50%) CpG sites and the number of gene coding CpG sites showing a 50% change in methylation in each of the 12 hyperprolactinemia patients

Case	CpG sites differentially methylated	CpG sites hypomethylated (< 50%)	CpG sites hypermethylated (> 50%)
DBN 6	166	122	44
DBN 7	156	116	40
DBN 8	167	113	54
DBN 16	194	155	39
DBN 30	171	139	32
DBN 39	161	119	42
DBN 51	164	118	44
DBN 54	181	153	28
DBN 68	164	118	46
DBN 75	182	149	33
DBN 92	169	109	60
DBN 94	152	105	47

DBN: data base number; CpG: 5-cytosine-phosphate-guanine-3

Declarations

Author contributions

AKK: Data curation, Formal analysis, Investigation, Software, Validation, Visualization, Writing—original draft, Writing—review & editing. AH: Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing—review & editing. MJ: Methodology, Project administration, Resources, Supervision, Validation. JBS: Resources, Supervision, Validation. All authors read and approved the submitted version.

Conflicts of interest

The authors declare that they have no conflicts of interest.

Ethical approval

Ethical clearance for the study was obtained from the Institute Ethics Committee, AIIMS, New Delhi, India (IESC/T-63/21.01.2015, RT-39/01.04.2015). All procedures performed in the study involving human participants were in accordance with the ethical standards of the institutional ethical committee. The study complies with the Declaration of Helsinki.

Consent to participate

Informed consent to participate in the study was obtained from all participants.

Consent to publication

Informed consent to publication was obtained from relevant participants.

Availability of data and materials

Requests for accessing the datasets should be directed to [Amanpreet Kaur Kalsi, kalsi.amanpreetkaur@gmail.com].

Funding

This work was supported by the Department of Reproductive Biology, AIIMS. AKK was supported by the Council of Scientific & Industrial Research-University Grants Commission (CSIR-UGC) fellowship [23/06/2013(i)EU-V]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Copyright

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