Prediction performance of FLI, HSI, FSI, and ZJU index in age-stratified subgroups
Indices | Age < 50 (N = 1,655) | Age ≥ 50 (N = 2,911) | ||||||
---|---|---|---|---|---|---|---|---|
AUC (95% CI) | Cut-off | SN (%) | SP (%) | AUC (95% CI) | Cut-off | SN (%) | SP (%) | |
FLI | 0.840 (0.822–0.858) | 26.7 | 72.87 | 79.81 | 0.804 (0.789–0.818) | 22.5 | 80.41 | 66.98 |
HSI | 0.827 (0.808–0.845) | 33.0 | 75.28 | 73.29 | 0.774 (0.758–0.789) | 32.9 | 72.39 | 69.57 |
FSI | 0.843 (0.825–0.860) | 10.0 | 79.12 | 73.61 | 0.806 (0.792–0.821) | 13.6 | 79.29 | 67.55 |
ZJU index | 0.851 (0.833–0.868) | 35.0 | 73.58 | 80.23 | 0.808 (0.793–0.822) | 35.0 | 75.28 | 72.88 |
AUC: area under the receiver operating characteristic curve; 95% CI: 95% confidence interval; SN: sensitivity; SP: specificity; FLI: fatty liver index; HSI: hepatic steatosis index; FSI: Framingham Steatosis index; ZJU index: Zhejiang University index
We express gratitude to all staff at the Health Management Center of the Second Affiliated Hospital of Chongqing Medical University for their assistance during the data collection process.
BX: Formal analysis, Writing—original draft. CL: Investigation, Formal analysis. MC: Investigation, Data curation. YZ: Conceptualization, Project administration, Methodology, Supervision, Writing—review & editing. All authors read and approved the submitted version.
The authors declare that they have no conflicts of interest.
This study was approved by the Ethics Committee of the Second Affiliated Hospital of Chongqing Medical University (approval no.2020261).
Informed consent was obtained from all participants prior to participation.
Not applicable.
The raw data supporting the conclusions of this article will be made available by the authors, without undue reservation.
This work is supported by the Chongqing Talents Project [cstc2021ycjhbgzxm0150] and the Chongqing Science and Technology Commission Joint Medical Project [2021MSXM057]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
© The Author(s) 2024.