Exploration of Endocrine and Metabolic Diseases (EEMD) is a new open access journal. This Journal, at this moment free of charge, aims to provide an open forum for both basic and clinical topics in the field. Few areas in Biomedicine have seen such a dramatic development in recent years as the field of Endocrinology and Metabolism. In the mean time more than half a billion people in the world suffer from diabetes and metabolic disease, which constitutes a major challenge for our health care systems. Metabolic disease has also been the major risk factor for severe course of disease in the COVID-19 pandemic. Exploration and better understanding and improved treatment for diabetes and metabolic and endocrine diseases is therefore badly needed, not only for the scientific community but for our entire society. The Journal welcomes submissions for all areas of basic and clinical Endocrinology and Metabolism. This will include the interface to other comorbidities including mental diseases, cardiovascular disease and infections and cancer. The Journal will also aim to bridge the scientific community to innovations in translation to start-up companies and industry. EEMD will publish original articles reviews, clinical protocols, clinical studies, commentaries, perspectives editorials, notes on innovations that may change the management of patients in the field of Endocrinology and Metabolism. There will be on the regular bases special issues exploring recent advances in cutting edge research and novel topics in the field.