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  • Exploration of Medicine

    eISSN: 2692-3106
    EiC: Lindsay A. Farrer, USA
    Frequency: Continuous Publication
    APC: $2,000 per article (See APC Waivers and Discounts)
    Publishing Model: Open Access
    Peer Review Model: Single Blind
    Indexing & Archiving: Scopus, Google Scholar, DOAJ, CAS, Dimensions, Portico, etc. The journal is also the member of COPE.
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    Articles
    Open Access
    Original Article
    Right ventricular echocardiographic parameters predict severe sleep apnea syndrome in patients with heart failure
    Aim: The study aimed to determine which right ventricle echocardiography parameters were associated with severe sleep apnea syndrome in heart failure patients with sleep apnea syndrome. Meth [...] Read more.
    Saoussen Antit ... Lilia Zakhama
    Published: April 23, 2025 Explor Med. 2025;6:1001311
    DOI: https://doi.org/10.37349/emed.2025.1001311
    View:39
    Download:6
    Times Cited: 0
    Open Access
    Original Article
    Long-term neurological and otolaryngological sequelae of COVID-19: a retrospective study
    Aim: COVID-19, a multisystemic syndrome caused by SARS-CoV-2, often results in long-term complications collectively referred to as long COVID. This study explores the persistence of neurological  [...] Read more.
    Wael Abu Ruqa ... Antonio Minni
    Published: April 21, 2025 Explor Med. 2025;6:1001310
    DOI: https://doi.org/10.37349/emed.2025.1001310
    This article belongs to the special issue Emerging Infectious Diseases
    View:87
    Download:6
    Times Cited: 0
    Open Access
    Original Article
    Cytocompatibility and bone regeneration potential of chitosan-thiocolchicoside-lauric acid nanogel with insights into zebrafish toxicology
    Aim: The present study explored the bone regeneration potential of chitosan-thiocolchicoside-lauric (CTL) nanogel using MG-63 cell lines. The cytocompatibility of CTL nanogel was also studied usi [...] Read more.
    Ameena Mustafa ... Giuseppe Minervini
    Published: April 21, 2025 Explor Med. 2025;6:1001309
    DOI: https://doi.org/10.37349/emed.2025.1001309
    View:77
    Download:9
    Times Cited: 0
    Open Access
    Review
    Breath analysis using FTIR spectroscopy
    Breath analysis is a relatively new topic of study that has a lot of potential for both therapeutic and scientific applications. The volatile organic compounds (VOCs) found in breath are created int [...] Read more.
    Andrei A. Bunaciu, Hassan Y. Aboul-Enein
    Published: April 17, 2025 Explor Med. 2025;6:1001308
    DOI: https://doi.org/10.37349/emed.2025.1001308
    View:116
    Download:10
    Times Cited: 0
    Open Access
    Original Article
    Joint mobilization strategies for chronic ankle instability: comparing active and passive approaches in a randomized controlled trial
    Aim: This study aimed to evaluate the differential effects of active joint mobilization (AJM) versus traditional passive joint mobilization (PJM) in individuals with chronic ankle instability. We [...] Read more.
    Hyunjoong Kim ... Mingyun Ko
    Published: April 17, 2025 Explor Med. 2025;6:1001307
    DOI: https://doi.org/10.37349/emed.2025.1001307
    View:121
    Download:7
    Times Cited: 0
    Open Access
    Original Article
    Inflammatory mediators in nasal secretion in patients with bronchial asthma and allergic rhinitis with or without polyposis and hypertrophic sinonasal mucosa
    Aim: The pathogenetic mechanisms and predictors of the development of polyposis and hypertrophy of the sinonasal mucosa (SM) in patients with chronic allergic airway inflammation have not been cl [...] Read more.
    Svetlana Viktorovna Krasilnikova ... Nailya Iskhakovna Kubysheva
    Published: April 17, 2025 Explor Med. 2025;6:1001306
    DOI: https://doi.org/10.37349/emed.2025.1001306
    View:100
    Download:3
    Times Cited: 0
    Open Access
    Original Article
    A large-scale survey of cannabis use for sleep: preferred products and perceived effects in comparison to over-the-counter and prescription sleep aids
    Aim: Cannabis use for sleep-related problems is on the rise; however, little is known about the cannabis products people are using for sleep or the perceived effects of cannabis in comparison to  [...] Read more.
    Amanda Stueber, Carrie Cuttler
    Published: October 25, 2023 Explor Med. 2023;4:709–719
    DOI: https://doi.org/10.37349/emed.2023.00171
    This article belongs to the special issue Beyond Weed: Clinical Applications of Cannabis and Cannabinoids
    View:30667
    Download:179
    Open Access
    Review
    The potential anti-cancer effects of melatonin on breast cancer
    Melatonin is the primary hormone of the pineal gland that is secreted at night. It regulates many physiological functions, including the sleep-wake cycle, gonadal activity, free radical scavenging,  [...] Read more.
    Naba Kumar Das, Saptadip Samanta
    Published: February 25, 2022 Explor Med. 2022;3:112–127
    DOI: https://doi.org/10.37349/emed.2022.00078
    View:20131
    Download:274
    Open Access
    Review
    3D printing in biomedicine: advancing personalized care through additive manufacturing
    The integration of three-dimensional (3D) printing techniques into the domains of biomedical research and personalized medicine highlights the evolving paradigm shifts within contemporary healthcare [...] Read more.
    Kalyani Pathak ... Barbie Borthakur
    Published: December 29, 2023 Explor Med. 2023;4:1135–1167
    DOI: https://doi.org/10.37349/emed.2023.00200
    This article belongs to the special issue Exploration of 3D and 4D Printing in the Biomedical and Personalized Medicine Fields: Merits and Challenges
    View:18215
    Download:288
    Open Access
    Review
    The gut microbiome and the immune system
    The human body contains trillions of microbes which generally live in symbiosis with the host. The interaction of the gut microbiome with elements of the host immune system has far-reaching effects  [...] Read more.
    Tenzin Choden, Nathaniel Aviv Cohen
    Published: May 31, 2022 Explor Med. 2022;3:219–233
    DOI: https://doi.org/10.37349/emed.2022.00087
    View:17196
    Download:478
    Open Access
    Original Article
    Cannabis use in cancer patients: acute and sustained associations with pain, cognition, and quality of life
    Aim: Given the myriad of negative sequalae associated with cancer and its treatment, the palliative use of cannabis by cancer patients is increasingly of special interest. This research sought to e [...] Read more.
    Gregory Giordano ... Angela D. Bryan
    Published: April 26, 2023 Explor Med. 2023;4:254–271
    DOI: https://doi.org/10.37349/emed.2023.00138
    This article belongs to the special issue Beyond Weed: Clinical Applications of Cannabis and Cannabinoids
    View:14832
    Download:285
    Open Access
    Review
    Reactive oxygen species in cancer progression and its role in therapeutics
    The redox status in pathogenesis is critically regulated by careful balance between the generation of reactive oxygen species (ROS) and their elimination. Increased ROS level above the cellular tole [...] Read more.
    Ranjeet Singh, Partha Pratim Manna
    Published: February 22, 2022 Explor Med. 2022;3:43–57
    DOI: https://doi.org/10.37349/emed.2022.00073
    This article belongs to the special issue Reactive Oxygen Species (ROS) in Pathophysiological Conditions
    View:12781
    Download:386
    Open Access
    Perspective
    Reactive oxygen species may influence on the crossroads of stemness, senescence, and carcinogenesis in a cell via the roles of APRO family proteins
    Excessive reactive oxygen species (ROS) may cause oxidative stress which is involved in aging and in the pathogenesis of various human diseases. Whereas unregulated levels of the ROS may be harmful, regulated basal level of ROS is [...] Read more.
    Yuka Ikeda ... Satoru Matsuda
    Published: October 31, 2021 Explor Med. 2021;2:443–454
    DOI: https://doi.org/10.37349/emed.2021.00062
    This article belongs to the special issue Reactive Oxygen Species (ROS) in Pathophysiological Conditions
    View:6988
    Download:2252
    Open Access
    Perspective
    A budding concept with certain microbiota, anti-proliferative family proteins, and engram theory for the innovative treatment of colon cancer
    Inflammatory bowel disease (IBD) is a multifactorial chronic disease. Patients with IBD have an increased risk of developing colorectal cancer which has become a major health concern. IBD might exer [...] Read more.
    Yuka Ikeda ... Satoru Matsuda
    Published: October 27, 2022 Explor Med. 2022;3:468–478
    DOI: https://doi.org/10.37349/emed.2022.00108
    This article belongs to the special issue The Role of Gut Microbiota and its Metabolites in Gastrointestinal Diseases
    View:4465
    Download:1845
    Open Access
    Review
    Roles of poly(ADP-ribose) polymerase 1 and mitophagy in progeroid syndromes as well as physiological ageing
    Progeroid syndromes are characterized by clinical signs of premature ageing, which may contain several diseases such as Werner syndrome, Bloom syndrome, Rothmund-Thomson syndrome, Hutchinson-Gilford [...] Read more.
    Naoko Suga ... Satoru Matsuda
    Published: October 31, 2023 Explor Med. 2023;4:822–838
    DOI: https://doi.org/10.37349/emed.2023.00180
    This article belongs to the special issue Determinants of Exceptional Longevity
    View:2978
    Download:906
    Open Access
    Review
    The gut microbiome and the immune system
    The human body contains trillions of microbes which generally live in symbiosis with the host. The interaction of the gut microbiome with elements of the host immune system has far-reaching effects  [...] Read more.
    Tenzin Choden, Nathaniel Aviv Cohen
    Published: May 31, 2022 Explor Med. 2022;3:219–233
    DOI: https://doi.org/10.37349/emed.2022.00087
    View:17196
    Download:478
    Open Access
    Review
    Reactive oxygen species in cancer progression and its role in therapeutics
    The redox status in pathogenesis is critically regulated by careful balance between the generation of reactive oxygen species (ROS) and their elimination. Increased ROS level above the cellular tole [...] Read more.
    Ranjeet Singh, Partha Pratim Manna
    Published: February 22, 2022 Explor Med. 2022;3:43–57
    DOI: https://doi.org/10.37349/emed.2022.00073
    This article belongs to the special issue Reactive Oxygen Species (ROS) in Pathophysiological Conditions
    View:12781
    Download:386
    Open Access
    Review
    Nonalcoholic fatty liver disease and type 2 diabetes: pathophysiological mechanisms shared between the two faces of the same coin
    The pathophysiological mechanisms underlying the close relationship between nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM) are multiple, complex and only partially known. The purpose of this paper was [...] Read more.
    Carlo Acierno ... Ferdinando Carlo Sasso
    Published: October 30, 2020 Explor Med. 2020;1:287–306
    DOI: https://doi.org/10.37349/emed.2020.00019
    This article belongs to the special issue Exploring NAFLD/NASH
    View:9514
    Download:338
    Open Access
    Review
    Nonalcoholic fatty liver disease and type 2 diabetes: pathophysiological mechanisms shared between the two faces of the same coin
    The pathophysiological mechanisms underlying the close relationship between nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM) are multiple, complex and only partially known. The purpose of this paper was [...] Read more.
    Carlo Acierno ... Ferdinando Carlo Sasso
    Published: October 30, 2020 Explor Med. 2020;1:287–306
    DOI: https://doi.org/10.37349/emed.2020.00019
    This article belongs to the special issue Exploring NAFLD/NASH
    View:9514
    Download:338
    Open Access
    Review
    Reactive oxygen species in cancer progression and its role in therapeutics
    The redox status in pathogenesis is critically regulated by careful balance between the generation of reactive oxygen species (ROS) and their elimination. Increased ROS level above the cellular tole [...] Read more.
    Ranjeet Singh, Partha Pratim Manna
    Published: February 22, 2022 Explor Med. 2022;3:43–57
    DOI: https://doi.org/10.37349/emed.2022.00073
    This article belongs to the special issue Reactive Oxygen Species (ROS) in Pathophysiological Conditions
    View:12781
    Download:386
    Open Access
    Review
    PNPLA3 gene and kidney disease
    Chronic kidney disease (CKD) is a disease regularly seen in clinical practice. At present, CKD is described as a change of kidney structure and/or function and it is classified in relation to cause, values of glomerular filtration [...] Read more.
    Alessandro Mantovani, Chiara Zusi
    Published: February 29, 2020 Explor Med. 2020;1:42–50
    DOI: https://doi.org/10.37349/emed.2020.00004
    Open Access
    Review
    Nonalcoholic fatty liver disease and portal hypertension
    Nonalcoholic fatty liver disease (NAFLD) is a substantial and growing problem worldwide and has become the second most common indication for liver transplantation as it may progress to cirrhosis and develop complications from port [...] Read more.
    Marvin Ryou ... Gyorgy Baffy
    Published: June 29, 2020 Explor Med. 2020;1:149–169
    DOI: https://doi.org/10.37349/emed.2020.00011
    This article belongs to the special issue Exploring NAFLD/NASH
    View:9271
    Download:139
    Open Access
    Review
    3D printing in biomedicine: advancing personalized care through additive manufacturing
    The integration of three-dimensional (3D) printing techniques into the domains of biomedical research and personalized medicine highlights the evolving paradigm shifts within contemporary healthcare [...] Read more.
    Kalyani Pathak ... Barbie Borthakur
    Published: December 29, 2023 Explor Med. 2023;4:1135–1167
    DOI: https://doi.org/10.37349/emed.2023.00200
    This article belongs to the special issue Exploration of 3D and 4D Printing in the Biomedical and Personalized Medicine Fields: Merits and Challenges
    View:18215
    Download:288
    Open Access
    Original Article
    Identification of digital voice biomarkers for cognitive health
    Aim: Human voice contains rich information. Few longitudinal studies have been conducted to investigate the potential of voice to monitor cognitive health. The objective of this study is to identify voice biomarkers that are pr [...] Read more.
    Honghuang Lin ... Rhoda Au
    Published: December 31, 2020 Explor Med. 2020;1:406–417
    DOI: https://doi.org/10.37349/emed.2020.00028
    This article belongs to the special issue Digital Biomarkers: The New Frontier for Medicine and Research
    View:4792
    Download:103
    Special Issues