Information and communication technologies (ICTs) have transformed global connectivity, offering significant support to underserved populations and small businesses in developing nations. The integration of social media into the ICT landscape has further revolutionized communication and information sharing worldwide. However, despite its widespread adoption, the precise impact of social media on biomedical research remains uncertain. This manuscript seeks to examine the multifaceted roles of social media in healthcare, focusing on its applications in patient care, professional networking, education, organizational promotion, and public health programs. Additionally, it investigates social media’s significance in research, particularly its potential for data collection and analysis. A comprehensive literature review was undertaken to consolidate existing knowledge on social media’s utilization in healthcare and research. Various platforms, including social networking sites and academic networking sites, were assessed, along with their respective applications and consequences. Social media platforms have become essential tools in healthcare, facilitating professional networking, patient education, organizational promotion, and public health initiatives. In the realm of research, social media provides extensive opportunities for data collection, analysis, and collaboration, although challenges persist regarding privacy, data accuracy, and ethical considerations. The pervasive influence of social media in healthcare and research highlights its potential to enhance communication, engagement, and knowledge dissemination. However, careful adherence to ethical guidelines and privacy concerns is essential to maximize its benefits while minimizing risks. As social media continues to evolve, its role in shaping biomedical research and healthcare practices is anticipated to grow, necessitating ongoing exploration and adaptation by stakeholders.