• 8 results in Exploration of Drug Science
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    Mini Review
    Lactoferrin: a secret weapon in the war against pathogenic bacteria
    The excessive use of antibiotics to treat bacterial infectious diseases in all living beings has caused a global epidemic of bacterial resistance to antibiotics, leading to the emergence of multidru [...] Read more.
    Lucero Ruiz-Mazón ... Mireya de la Garza
    Published: October 21, 2024 Explor Drug Sci. 2024;2:734–743
    DOI: https://doi.org/10.37349/eds.2024.00072
    This article belongs to the special issue Bioactive Peptides: Pioneering Innovations in Latin American Research
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    Open Access
    Original Article
    Bicyclic peptide-enhanced covalent inhibitor of SARS-CoV-2 3CL protease
    Aim: Develop technology to apply bicyclic peptides for discovering covalent inhibitors of proteases and use this technology to create bicyclic peptide—warhead conjugates for targeting the sever [...] Read more.
    Qian Wang ... Shiyu Chen
    Published: October 17, 2024 Explor Drug Sci. 2024;2:719–733
    DOI: https://doi.org/10.37349/eds.2024.00071
    This article belongs to the special issue Bioactive Peptides discovery and development
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    Open Access
    Review
    Synthetic peptides as valuable and versatile tools for research: our 20 year journey in Chile
    According to the International Union of Pure and Applied Chemistry (IUPAC), peptides are small proteins with a size between 2 and 50 amino acids residues. They are ubiquitous across the evolutionary [...] Read more.
    Constanza Cárdenas ... Fanny Guzmán
    Published: October 15, 2024 Explor Drug Sci. 2024;2:701–718
    DOI: https://doi.org/10.37349/eds.2024.00070
    This article belongs to the special issue Bioactive Peptides: Pioneering Innovations in Latin American Research
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    Times Cited: 0
    Open Access
    Perspective
    Foundational contributions of Svetlana Mojsov to the GLP-1 field
    Biochemist Svetlana Mojsov, both as a graduate student at The Rockefeller University under the mentorship of Bruce Merrifield during the 1970s, and as an independent investigator at the Massachusett [...] Read more.
    George Barany, Michael J. Barany
    Published: October 3, 2024 Explor Drug Sci. 2024;2:688–700
    DOI: https://doi.org/10.37349/eds.2024.00069
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    Original Article
    Prediction of absolute bioavailability of medicines in children: based on predicted pediatric clearance from adults
    Aim: The objective of this study was to evaluate the predictive performance of a proposed method to predict absolute bioavailability of medicines in children (infants to adolescents). Method [...] Read more.
    Iftekhar Mahmood
    Published: September 30, 2024 Explor Drug Sci. 2024;2:677–687
    DOI: https://doi.org/10.37349/eds.2024.00068
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    Review
    Effect of combined oral contraceptives on menstrual migraine frequency and severity: a narrative review
    Migraine, a commonly occurring neurological disorder, disproportionately affects women during their reproductive years, and its symptoms are often intensified by hormonal fluctuations. This narrativ [...] Read more.
    Yethindra Vityala ... Krishna Chaitanya Meduri
    Published: September 30, 2024 Explor Drug Sci. 2024;2:666–676
    DOI: https://doi.org/10.37349/eds.2024.00067
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    Review
    21st century Latin American synthetic peptides for their application in antivenom production
    Envenomation caused by snakes, scorpions, and spiders represents a serious public health problem in Latin America. The antivenoms used for its treatment are produced by immunizing horses repeatedly  [...] Read more.
    Jésica A. Rodríguez ... Silvia A. Camperi
    Published: September 30, 2024 Explor Drug Sci. 2024;2:648–665
    DOI: https://doi.org/10.37349/eds.2024.00066
    This article belongs to the special issue Bioactive Peptides: Pioneering Innovations in Latin American Research
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    Times Cited: 0
    Open Access
    Original Article
    Properties of new polycationic bacteriochlorin photosensitizers: cytotoxicity and interaction with biofilms
    Aim: Biofilms of pathogenic bacteria are phenotypically resistant to antibiotics and other antimicrobial agents, host immune systems, and adverse environmental conditions, and are responsible for [...] Read more.
    Irina Tiganova ... Yulia Romanova
    Published: September 27, 2024 Explor Drug Sci. 2024;2:632–647
    DOI: https://doi.org/10.37349/eds.2024.00065
    This article belongs to the special issue Discovery and development of new antibacterial compounds
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    Times Cited: 0